ID   RER1_SACPS              Reviewed;         188 AA.
AC   P79003;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein RER1;
DE   AltName: Full=Retention of ER proteins 1;
GN   Name=RER1;
OS   Saccharomyces pastorianus (Lager yeast) (Saccharomyces cerevisiae x
OS   Saccharomyces eubayanus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=27292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Andersen T., Nilsson-Tillgren T.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the retrieval of endoplasmic reticulum membrane
CC       proteins from the early Golgi compartment. Required for correct
CC       localization of SEC12, SEC71 and SEC63 in the endoplasmic reticulum (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
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DR   EMBL; Z86109; CAB06798.1; -; Genomic_DNA.
DR   AlphaFoldDB; P79003; -.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051179; P:localization; IEA:UniProt.
DR   InterPro; IPR004932; Rer1.
DR   PANTHER; PTHR10743; PTHR10743; 1.
DR   Pfam; PF03248; Rer1; 1.
DR   PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..188
FT                   /note="Protein RER1"
FT                   /id="PRO_0000207592"
FT   TRANSMEM        43..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   188 AA;  22159 MW;  8F923B39A738AFE8 CRC64;
     MDYDSPDPMN GASSNALIAK MNSAKLLYQH YLDKVTPHAK QRWAVLGGLL CLFMVRITMA
     EGWYVICYGL GLFLLNQFLA FLTPKFDMSL QQDEENNELE AGEKSEEFRP FIRRLPEFKF
     WYNSIRATVI SLVLSLFSIF DIPVFWPILL MYFVLLFFLT MRRQIQHMMK YRYIPLDIGK
     KKYSHPSN