RER5_ARATH
ID RER5_ARATH Reviewed; 735 AA.
AC Q9SIY5; Q0WVB8;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Protein RETICULATA-RELATED 5, chloroplastic {ECO:0000303|PubMed:23596191};
DE Flags: Precursor;
GN Name=RER5 {ECO:0000303|PubMed:23596191};
GN OrderedLocusNames=At2g40400 {ECO:0000312|Araport:AT2G40400};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, GENE FAMILY, NOMENCLATURE, AND DISRUPTION PHENOTYPE.
RX PubMed=23596191; DOI=10.1104/pp.113.217323;
RA Perez-Perez J.M., Esteve-Bruna D., Gonzalez-Bayon R., Kangasjarvi S.,
RA Caldana C., Hannah M.A., Willmitzer L., Ponce M.R., Micol J.L.;
RT "Functional redundancy and divergence within the Arabidopsis RETICULATA-
RT RELATED gene family.";
RL Plant Physiol. 162:589-603(2013).
CC -!- FUNCTION: May play a role in leaf development.
CC {ECO:0000305|PubMed:23596191}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane
CC {ECO:0000250|UniProtKB:Q9C9Z2}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:23596191}.
CC -!- SIMILARITY: Belongs to the RETICULATA family. {ECO:0000305}.
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DR EMBL; AC007020; AAD25674.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09822.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09823.1; -; Genomic_DNA.
DR EMBL; AF410285; AAK95271.1; -; mRNA.
DR EMBL; AY102131; AAM26698.1; -; mRNA.
DR EMBL; AK226837; BAE98930.1; -; mRNA.
DR PIR; A84829; A84829.
DR RefSeq; NP_565930.1; NM_129600.4.
DR RefSeq; NP_850329.1; NM_179998.2.
DR AlphaFoldDB; Q9SIY5; -.
DR STRING; 3702.AT2G40400.2; -.
DR PaxDb; Q9SIY5; -.
DR PRIDE; Q9SIY5; -.
DR ProteomicsDB; 226179; -.
DR EnsemblPlants; AT2G40400.1; AT2G40400.1; AT2G40400.
DR EnsemblPlants; AT2G40400.2; AT2G40400.2; AT2G40400.
DR GeneID; 818633; -.
DR Gramene; AT2G40400.1; AT2G40400.1; AT2G40400.
DR Gramene; AT2G40400.2; AT2G40400.2; AT2G40400.
DR KEGG; ath:AT2G40400; -.
DR Araport; AT2G40400; -.
DR TAIR; locus:2063136; AT2G40400.
DR eggNOG; ENOG502QPUQ; Eukaryota.
DR HOGENOM; CLU_011621_0_0_1; -.
DR InParanoid; Q9SIY5; -.
DR OMA; YICIRSH; -.
DR OrthoDB; 1073523at2759; -.
DR PhylomeDB; Q9SIY5; -.
DR PRO; PR:Q9SIY5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIY5; baseline and differential.
DR Genevisible; Q9SIY5; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IMP:TAIR.
DR GO; GO:0009741; P:response to brassinosteroid; IMP:TAIR.
DR CDD; cd14727; ChanN-like; 1.
DR InterPro; IPR007314; Cofac_haem-bd_dom.
DR InterPro; IPR021825; RETICULATA-related.
DR Pfam; PF04187; Cofac_haem_bdg; 1.
DR Pfam; PF11891; RETICULATA-like; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Developmental protein; Membrane; Plastid; Reference proteome;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..75
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 76..735
FT /note="Protein RETICULATA-RELATED 5, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433444"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 582..602
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 714..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 650
FT /note="I -> V (in Ref. 4; BAE98930)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 735 AA; 80701 MW; 6D042390AFF8D133 CRC64;
MKPTTNGGLL ASQSSSSFSF PRFRGQLPII FSANNNQKKK NLPNPNVVTL CLHSHSNVSS
SQIAVTRRAI LVAPPLLAAA ASLFLSISSA ASAETSAESV ALPPVATAPP PPPVEKEEAI
TSRIYDASVL GEPMAVGKDK KRVWEKLLNA RIVYLGEAEQ VPTRDDKVLE LEIVRNLRKR
CIESDRQLSL ALEAFPLDLQ EQLNQYMDKR MDGEVLKSYV SHWPVQRWQE YEPLLSYCRD
NGVKLIACGT PLKVLRTVQA EGIRGLSESE RKLYTPPAGS GFISGFTSFS RSSSLNMNPL
TQIVPFGPSS YLSAQARVVE DHTMSQVIVQ AVADGGGTGM LVVVTGANHV EYGSRGTGLP
ARISRKIPKK SQLVVLLDPE RQFLRKEGES PVADFLWYSA ARPCSRNCFD RAEIARVMNA
AGRRRDALPQ DIQKGLDLGL VSPEILQNFF DLEQYPLISE LTQRFQGFRE RLLADPKFLN
RLAIEEAISI TTTLVAQYEK RKENFFEELD YVITDSVRAS VVDFFTVWLP APTLSFISYA
DETIGPNSID ALRGLLGSIP DNAFQKSLGG QEWTLSLRIA SVIIGGLKLA GVGVVSSFAA
VGSSNALYAI RKFIKPELGV GEQAKRSPML KTALVYGGYL GTSSNIRYQI IAGLIEHRIS
DELSSQPLLV NMISFVVRVA NSYFGTQQWI DLARSTGLQT QKSVTTSNQI PEVASQSTVE
YSTTEEASMD DLKNQ
