RER6_ARATH
ID RER6_ARATH Reviewed; 745 AA.
AC Q8RWG3; Q9LYM7;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Protein RETICULATA-RELATED 6, chloroplastic {ECO:0000303|PubMed:23596191};
DE Flags: Precursor;
GN Name=RER6 {ECO:0000303|PubMed:23596191};
GN OrderedLocusNames=At3g56140 {ECO:0000312|Araport:AT3G56140};
GN ORFNames=F18O21_100 {ECO:0000312|EMBL:CAB87413.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, GENE FAMILY, NOMENCLATURE, AND DISRUPTION PHENOTYPE.
RX PubMed=23596191; DOI=10.1104/pp.113.217323;
RA Perez-Perez J.M., Esteve-Bruna D., Gonzalez-Bayon R., Kangasjarvi S.,
RA Caldana C., Hannah M.A., Willmitzer L., Ponce M.R., Micol J.L.;
RT "Functional redundancy and divergence within the Arabidopsis RETICULATA-
RT RELATED gene family.";
RL Plant Physiol. 162:589-603(2013).
CC -!- FUNCTION: May play a role in leaf development.
CC {ECO:0000305|PubMed:23596191}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane
CC {ECO:0000250|UniProtKB:Q9C9Z2}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:23596191}.
CC -!- SIMILARITY: Belongs to the RETICULATA family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB87413.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL163763; CAB87413.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE79485.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64059.1; -; Genomic_DNA.
DR EMBL; AY093111; AAM13110.1; -; mRNA.
DR EMBL; BT010340; AAQ56783.1; -; mRNA.
DR EMBL; AK227110; BAE99161.1; -; mRNA.
DR PIR; T47731; T47731.
DR RefSeq; NP_001326110.1; NM_001339772.1.
DR RefSeq; NP_191173.2; NM_115472.5.
DR AlphaFoldDB; Q8RWG3; -.
DR STRING; 3702.AT3G56140.1; -.
DR PaxDb; Q8RWG3; -.
DR PRIDE; Q8RWG3; -.
DR ProteomicsDB; 234916; -.
DR EnsemblPlants; AT3G56140.1; AT3G56140.1; AT3G56140.
DR EnsemblPlants; AT3G56140.3; AT3G56140.3; AT3G56140.
DR GeneID; 824780; -.
DR Gramene; AT3G56140.1; AT3G56140.1; AT3G56140.
DR Gramene; AT3G56140.3; AT3G56140.3; AT3G56140.
DR KEGG; ath:AT3G56140; -.
DR Araport; AT3G56140; -.
DR TAIR; locus:2078446; AT3G56140.
DR eggNOG; ENOG502QPUQ; Eukaryota.
DR HOGENOM; CLU_011621_0_0_1; -.
DR InParanoid; Q8RWG3; -.
DR OrthoDB; 1073523at2759; -.
DR PhylomeDB; Q8RWG3; -.
DR PRO; PR:Q8RWG3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8RWG3; baseline and differential.
DR Genevisible; Q8RWG3; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR CDD; cd14727; ChanN-like; 1.
DR InterPro; IPR007314; Cofac_haem-bd_dom.
DR InterPro; IPR021825; RETICULATA-related.
DR Pfam; PF04187; Cofac_haem_bdg; 1.
DR Pfam; PF11891; RETICULATA-like; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Developmental protein; Membrane; Plastid; Reference proteome;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..50
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 51..745
FT /note="Protein RETICULATA-RELATED 6, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433445"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 591..611
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 94..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..124
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 745 AA; 82252 MW; 376F5BCE4D0B4045 CRC64;
MKLTTNDLFA SQPLFHCPCS SSSRPRRRRF YGLHFPINLT SEKNNSLSIV ALSDSDLPSR
TAFSRRAFLL APPLLVSAAS LFLKPSVSLA SEESSSATVT SPAESAAPPP PPATTTPSPP
PPVNKEETIT SRIYDATAIG EPMAMGKDKK KVWEKLLNAR VVYLGEAEQV PTKDDKELEL
EIVRNLRKRC VESERQISVA LEAFPLDLQD QLNQYMDKRM DGETLKSYVT HWPAQRWQEY
EPLLSYCRDN SVRLIACGTP LKVLRTVQAE GIRGLSKSER KLYTPPAGSG FISGFSSFSR
RSTFDMSLPT QIVPFGPSSY LSAQARVVED HTMSQVILQA VADGGGTGLL LVVTGASHVE
YGSRGTGLPA RISRKFPKKN QVVVLLDPER QFLRREGETP VADFLWYSAA RPCSRNCFDR
AEIARVMNAA GRRRDALPPD IQNGLDLGLV SPEVLQNLFD LEQYPLISEL TQRFQGFRER
LLADPKFLNR LAIEEAISIT TTLIAQYEKR KENFFEEIDY VITDTVRGSV VDFFTVWLPA
PTLSFLSYAD ETTGPDSIDA LRGLLGSIPD NAFQKSLAGR EWNLNLRIAS VIVGGLKLAG
VGVVSSFAAV GASNALNIAR KVIKPELVVA EKPKRSPLLK TAMVYGGFLG TSANLRYQII
AGLIEHRLSD ELSSQPLLVN AISFVVRTLN SYFGTQQWID LARSTGLQTQ KSIPASKEIS
EALEEPTVEC DTTTEEESID KLNNQ
