ID   RESA_PLAFP              Reviewed;         304 AA.
AC   Q26005;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Ring-infected erythrocyte surface antigen;
DE   Flags: Fragment;
GN   Name=RESA;
OS   Plasmodium falciparum (isolate Palo Alto / Uganda).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=57270;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8206141; DOI=10.1006/expr.1994.1046;
RA   Kun J., Leet M., Anthony R.L., Kun J.E., Anders R.F.;
RT   "Plasmodium falciparum: a region of polymorphism in the 3' end of the gene
RT   for the ring-infected erythrocyte surface antigen.";
RL   Exp. Parasitol. 78:418-421(1994).
CC   -!- FUNCTION: May disrupt the normal intermolecular interactions of the
CC       cytoplasmic domain of band 3 and thereby facilitate the invagination of
CC       the red cell membrane which is necessary for the formation of the
CC       parasitophorous vacuole. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein;
CC       Cytoplasmic side. Note=Probably located on the cytoplasmic face of the
CC       membrane where it associates with components of the membrane skeleton.
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DR   EMBL; X55124; CAA38918.1; -; Genomic_DNA.
DR   PIR; S21342; S21342.
DR   AlphaFoldDB; Q26005; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026894; DnaJ_X.
DR   Pfam; PF14308; DnaJ-X; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycoprotein; Malaria; Membrane; Repeat.
FT   CHAIN           <1..>304
FT                   /note="Ring-infected erythrocyte surface antigen"
FT                   /id="PRO_0000071161"
FT   REGION          142..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..298
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        18
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        22
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
FT   NON_TER         304
SQ   SEQUENCE   304 AA;  35225 MW;  54807B86C85AD75C CRC64;
     NSITYNFENI NSNVDNGNQS KNISDLSYTD QKEILEKIVS YIVDISLYDI ENTALNAAEQ
     LLSDNSVDEK TLKKRAQSLK KLSSIMERYA GGKRNDKKAK KYDTQDVVGY IMHGISTINK
     EMKNQNENVP EHVQHNAEAN VEHDAEENVE HDAEENVEHD AEENAEENVE ENVEEVEENV
     EENVEENVEE NVEENVEENV EENVEEVEEN VEENVEENVE ENVEENVEEN VEENVEENVE
     ENVEENVEEY DEENVEEVEE NVEENVEENV EENVEENVEE NVEENVEENV EEYDEENVEE
     HNGI