ID   RETM_ANOGA              Reviewed;         684 AA.
AC   Q7PWB1;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 4.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Protein real-time;
GN   Name=retm {ECO:0000250|UniProtKB:Q9VMD6}; ORFNames=AGAP009029;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1] {ECO:0000312|EMBL:EAA14774.4}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000312|EMBL:EAA14774.4};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9VMD6}.
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DR   EMBL; AAAB01008984; EAA14774.4; -; Genomic_DNA.
DR   RefSeq; XP_319779.4; XM_319779.4.
DR   AlphaFoldDB; Q7PWB1; -.
DR   SMR; Q7PWB1; -.
DR   GeneID; 1279987; -.
DR   KEGG; aga:AgaP_AGAP009029; -.
DR   CTD; 1279987; -.
DR   VEuPathDB; VectorBase:AGAP009029; -.
DR   InParanoid; Q7PWB1; -.
DR   OrthoDB; 1133487at2759; -.
DR   PhylomeDB; Q7PWB1; -.
DR   Proteomes; UP000007062; Chromosome 3R.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR011074; CRAL/TRIO_N_dom.
DR   InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR   InterPro; IPR036598; GOLD_dom_sf.
DR   InterPro; IPR006797; PRELI/MSF1_dom.
DR   Pfam; PF00650; CRAL_TRIO; 1.
DR   Pfam; PF03765; CRAL_TRIO_N; 1.
DR   Pfam; PF04707; PRELI; 1.
DR   SMART; SM01100; CRAL_TRIO_N; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF101576; SSF101576; 1.
DR   SUPFAM; SSF46938; SSF46938; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
DR   PROSITE; PS50904; PRELI_MSF1; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..684
FT                   /note="Protein real-time"
FT                   /id="PRO_0000312683"
FT   DOMAIN          2..178
FT                   /note="PRELI/MSF1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00158"
FT   DOMAIN          297..474
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   DOMAIN          537..684
FT                   /note="GOLD"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   684 AA;  78012 MW;  6C179C21298ACB90 CRC64;
     MVQKYESPVR IYKYPFELVV AGFRNFCRQK SVLRRGKVCE MGSIFGEAKT TTNTWCIRRW
     SFAVVCKKII IEEFLFLFVK HQLYQYLCNH IVNIEYAYHK PYNSFATRVE IFEKCRYYAH
     PENPDWTCFD QTATLDIKNF FGIEHSMEKM GMKQYTQTTL KGKEIIEFFV NELKQEGITH
     VDRWVDDATV TSTTAGAATN TTPPEKPPLC RDNSILDADY IAKYLGQLTP LQESKLVQLR
     KRFEHGTSEH PEPDYQTLLR FLRARDFSID KATGMLQESL QWRKEQRIDS ILGEYKTPAV
     VEKYFPGGWH HHDKDGRPLY ILRLGTMDVK GLLKSVGEDE LLKLTLHICE EGLRLMKEAT
     KLFGKPVWNW CLLVDLDGLS MRHLWRPGVK ALLRIIETVE TNYPETMGRV LIVRAPRVFP
     VLWTIVSTFI DENTRSKFLF FGGPDCMHAE DGIEQYIDTD KIPSFLGGSC NVIDCPIVAL
     PNSVCVNRPV SSSSFDSSIV KLSPPPALSP HAFCSVATAI AYSLHFATLN GGIAHDHHGL
     YKAVDLKPGQ LFELLIRNTD PKSVLTWDFE VLKNDTLFAV FHTEKEIEQS GNDDFSSVFD
     GPDFKEGTNY KKIEQSVKCR PKEGVQGSHE MASTGTYVLQ WMCPPSCDGP AQLMYFHEIL
     SSANYKGSMT SLQSGFSSNS LQSR