REV7_ARATH
ID REV7_ARATH Reviewed; 215 AA.
AC Q94FL5; Q9FX75;
DT 13-NOV-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=DNA polymerase zeta processivity subunit;
DE AltName: Full=Revertibility protein 7 homolog;
DE Short=AtREV7;
DE Short=REV7 homolog;
GN Name=REV7; OrderedLocusNames=At1g16590; ORFNames=F19K19.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Wilson L.J., Vonarx E.J., Straffon A.F., Kunz B.A.;
RT "AtREV7 is a putative plant homolog of the yeast REV7 translesion synthesis
RT gene.";
RL Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION.
RX PubMed=15908599; DOI=10.1104/pp.105.060236;
RA Takahashi S., Sakamoto A., Sato S., Kato T., Tabata S., Tanaka A.;
RT "Roles of Arabidopsis AtREV1 and AtREV7 in translesion synthesis.";
RL Plant Physiol. 138:870-881(2005).
CC -!- FUNCTION: Regulatory subunit of the error prone DNA polymerase zeta.
CC Involved in damage-tolerance mechanisms through translesion DNA
CC synthesis (By similarity). {ECO:0000250, ECO:0000269|PubMed:15908599}.
CC -!- SUBUNIT: Forms DNA polymerase zeta with REV3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MAD2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG10822.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF372829; AAK69719.1; -; mRNA.
DR EMBL; AC011808; AAG10822.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29474.1; -; Genomic_DNA.
DR EMBL; BT024601; ABD42999.1; -; mRNA.
DR EMBL; AK175235; BAD42998.1; -; mRNA.
DR PIR; B86301; B86301.
DR RefSeq; NP_564002.1; NM_101522.4.
DR AlphaFoldDB; Q94FL5; -.
DR SMR; Q94FL5; -.
DR STRING; 3702.AT1G16590.1; -.
DR PaxDb; Q94FL5; -.
DR PRIDE; Q94FL5; -.
DR ProteomicsDB; 236237; -.
DR EnsemblPlants; AT1G16590.1; AT1G16590.1; AT1G16590.
DR GeneID; 838228; -.
DR Gramene; AT1G16590.1; AT1G16590.1; AT1G16590.
DR KEGG; ath:AT1G16590; -.
DR Araport; AT1G16590; -.
DR TAIR; locus:2017958; AT1G16590.
DR eggNOG; KOG3186; Eukaryota.
DR HOGENOM; CLU_050394_3_0_1; -.
DR InParanoid; Q94FL5; -.
DR OMA; CEDFPWI; -.
DR OrthoDB; 1630737at2759; -.
DR PhylomeDB; Q94FL5; -.
DR PRO; PR:Q94FL5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q94FL5; baseline and differential.
DR Genevisible; Q94FL5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016035; C:zeta DNA polymerase complex; IBA:GO_Central.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:TAIR.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0010224; P:response to UV-B; IMP:TAIR.
DR Gene3D; 3.30.900.10; -; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; PTHR11842; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; SSF56019; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 2: Evidence at transcript level;
KW DNA damage; DNA repair; Nucleus; Reference proteome.
FT CHAIN 1..215
FT /note="DNA polymerase zeta processivity subunit"
FT /id="PRO_0000424419"
FT DOMAIN 10..193
FT /note="HORMA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00109"
SQ SEQUENCE 215 AA; 24393 MW; A13A36231791FA0E CRC64;
MSRKDDNQSG EVGRTLVDFM EVAITMIVYL KGFYPSAAFE RRRYMNVVVQ RARHPELRDY
IHSAASGLLP FIEKGLVERV AVVFFSEDNV PVERFIFKIT IKPSCAALVE EGQLEFALRS
FLIKLSVSKS LVKPLPLNCR WEVTAYLRSL PQVGSSKEAE LWIPTDTKQW QNPPVLTPVK
SLNSEPLCLQ LYLEHPSLSE PLNLVNPEDV APHDP
