ID   RF1_METM5               Reviewed;         419 AA.
AC   A4FX39;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Peptide chain release factor subunit 1 {ECO:0000255|HAMAP-Rule:MF_00424};
DE   AltName: Full=Translation termination factor aRF1 {ECO:0000255|HAMAP-Rule:MF_00424};
GN   Name=prf1 {ECO:0000255|HAMAP-Rule:MF_00424}; OrderedLocusNames=MmarC5_0453;
OS   Methanococcus maripaludis (strain C5 / ATCC BAA-1333).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=402880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C5 / ATCC BAA-1333;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C.,
RA   Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of chromosome of Methanococcus maripaludis C5.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Directs the termination of nascent peptide synthesis
CC       (translation) in response to the termination codons UAA, UAG and UGA.
CC       {ECO:0000255|HAMAP-Rule:MF_00424}.
CC   -!- SUBUNIT: Heterodimer of two subunits, one of which binds GTP.
CC       {ECO:0000255|HAMAP-Rule:MF_00424}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00424}.
CC   -!- SIMILARITY: Belongs to the eukaryotic release factor 1 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00424}.
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DR   EMBL; CP000609; ABO34768.1; -; Genomic_DNA.
DR   RefSeq; WP_011868223.1; NC_009135.1.
DR   AlphaFoldDB; A4FX39; -.
DR   SMR; A4FX39; -.
DR   STRING; 402880.MmarC5_0453; -.
DR   DNASU; 4928774; -.
DR   EnsemblBacteria; ABO34768; ABO34768; MmarC5_0453.
DR   GeneID; 4928774; -.
DR   KEGG; mmq:MmarC5_0453; -.
DR   eggNOG; arCOG01742; Archaea.
DR   HOGENOM; CLU_035759_3_0_2; -.
DR   OMA; GQEMEVV; -.
DR   OrthoDB; 32191at2157; -.
DR   Proteomes; UP000000253; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.30.420.60; -; 1.
DR   Gene3D; 3.30.960.10; -; 1.
DR   HAMAP; MF_00424; Rel_fact_arch_1; 1.
DR   InterPro; IPR042226; eFR1_2_sf.
DR   InterPro; IPR005140; eRF1_1_Pelota.
DR   InterPro; IPR024049; eRF1_1_sf.
DR   InterPro; IPR005141; eRF1_2.
DR   InterPro; IPR005142; eRF1_3.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR020918; Peptide_chain-rel_aRF1.
DR   InterPro; IPR004403; Peptide_chain-rel_eRF1/aRF1.
DR   PANTHER; PTHR10113; PTHR10113; 1.
DR   Pfam; PF03463; eRF1_1; 1.
DR   Pfam; PF03464; eRF1_2; 1.
DR   Pfam; PF03465; eRF1_3; 1.
DR   SMART; SM01194; eRF1_1; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF55481; SSF55481; 1.
DR   TIGRFAMs; TIGR03676; aRF1/eRF1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Protein biosynthesis.
FT   CHAIN           1..419
FT                   /note="Peptide chain release factor subunit 1"
FT                   /id="PRO_1000060104"
SQ   SEQUENCE   419 AA;  47202 MW;  A61EB2D1F70B1171 CRC64;
     MSGNSSTDMY LFKKSLKELK GKKGKGTELI SVYVPAGRRL SDISQYLRQE LSQSSNIKSK
     TTMKNVQSAI EVILQRLKLL KEPLEMGVII FAGMIPRGGP GTEKMEVYVL EPPEPVKTFV
     YRCDSLFYTD PLEDFIQDTE VYGVILVDRN EATIGTVKGK TITVLKKLTS GVPGKFKAGG
     QSARRLERLI DDAAHQFMVR IGEYATESFM PILEEKKLKG LLLGGPGNTK NEFAEKDYLH
     HELKKKIIDT FDLCYTEEFG IRELLDKASD LLRDLDLMKE KNLIQKFFKE LIKDDGGLSA
     YGEAQVMKYL EMGAIDTLIV TEDIGITRVT VKCNNCDYAQ EVNVKTNEMF KFEEQLKTKA
     CPTCGGAMYI DEEKDIIEHL SDLCHMHNTD IIVVSTDTEE GSQISRAFKG MAAILRYKL