ID   RF1_PASMU               Reviewed;         360 AA.
AC   P57852;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Peptide chain release factor 1;
DE            Short=RF-1;
GN   Name=prfA; OrderedLocusNames=PM0555;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: Peptide chain release factor 1 directs the termination of
CC       translation in response to the peptide chain termination codons UAG and
CC       UAA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Methylated by PrmC. Methylation increases the termination
CC       efficiency of RF1 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor
CC       family. {ECO:0000305}.
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DR   EMBL; AE004439; AAK02639.1; -; Genomic_DNA.
DR   RefSeq; WP_005751423.1; NC_002663.1.
DR   AlphaFoldDB; P57852; -.
DR   SMR; P57852; -.
DR   STRING; 747.DR93_1333; -.
DR   EnsemblBacteria; AAK02639; AAK02639; PM0555.
DR   KEGG; pmu:PM0555; -.
DR   HOGENOM; CLU_036856_0_1_6; -.
DR   OMA; ISDHRVG; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00093; Rel_fac_1; 1.
DR   InterPro; IPR005139; PCRF.
DR   InterPro; IPR000352; Pep_chain_release_fac_I.
DR   InterPro; IPR045853; Pep_chain_release_fac_I_sf.
DR   InterPro; IPR004373; RF-1.
DR   Pfam; PF03462; PCRF; 1.
DR   Pfam; PF00472; RF-1; 1.
DR   SMART; SM00937; PCRF; 1.
DR   SUPFAM; SSF75620; SSF75620; 1.
DR   TIGRFAMs; TIGR00019; prfA; 1.
DR   PROSITE; PS00745; RF_PROK_I; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methylation; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..360
FT                   /note="Peptide chain release factor 1"
FT                   /id="PRO_0000177719"
FT   REGION          284..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         235
FT                   /note="N5-methylglutamine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   360 AA;  40653 MW;  5555E63BE68E71EE CRC64;
     MKPTIISKLE SLKERHEELE ALLGEASVIS DQDKFRAYSK EYAQLEDVVK CFARWNQLNS
     NMEEAQLLLD DPSMKEMAQE EIEACKTEIE QVEQQLQILL LPKDPNDEYN CYLEIRAGTG
     GDEAGIFAGD LFRMYSRYAE SKRWKVEVLS ANESEQGGYK EIIVKVNGEG VYGQLKFESG
     GHRVQRVPKT ESQGRIHTSA CTVAVMPELP ESELPEINPS DLRIDTYRSS GAGGQHVNTT
     DSAVRITHIP TGIVVECQDE RSQHKNKAKA MSVLASRIVQ AEKERQEQAQ ADTRRNLLGS
     GDRSDKIRTY NYPQGRVTDH RINLTVYRLD EVMNGKIDEL IQPIITEYQA DQLAALSEQA