AAIP_WHEAT
ID AAIP_WHEAT Reviewed; 332 AA.
AC Q02066;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Abscisic acid-inducible protein kinase;
DE EC=2.7.11.1;
DE Flags: Fragment;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Brevor; TISSUE=Seed;
RX PubMed=1438207; DOI=10.1073/pnas.89.21.10183;
RA Anderberg R.J., Walker-Simmons M.K.;
RT "Isolation of a wheat cDNA clone for an abscisic acid-inducible transcript
RT with homology to protein kinases.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:10183-10187(1992).
CC -!- FUNCTION: Involved in water-stress responses.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1;
CC -!- INDUCTION: By abscisic acid (ABA) and dehydration.
CC -!- PTM: Autophosphorylated. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; M94726; AAA96325.1; -; mRNA.
DR PIR; A46408; A46408.
DR AlphaFoldDB; Q02066; -.
DR SMR; Q02066; -.
DR STRING; 4565.Traes_2AL_2FF604DA9.2; -.
DR EnsemblPlants; TraesCAD_scaffold_034592_01G000300.1; TraesCAD_scaffold_034592_01G000300.1; TraesCAD_scaffold_034592_01G000300.
DR EnsemblPlants; TraesCLE_scaffold_034604_01G000300.1; TraesCLE_scaffold_034604_01G000300.1; TraesCLE_scaffold_034604_01G000300.
DR EnsemblPlants; TraesPAR_scaffold_030712_01G000300.1; TraesPAR_scaffold_030712_01G000300.1; TraesPAR_scaffold_030712_01G000300.
DR EnsemblPlants; TraesROB_scaffold_036448_01G000300.1; TraesROB_scaffold_036448_01G000300.1; TraesROB_scaffold_036448_01G000300.
DR EnsemblPlants; TraesWEE_scaffold_093303_01G000100.1; TraesWEE_scaffold_093303_01G000100.1; TraesWEE_scaffold_093303_01G000100.
DR Gramene; TraesCAD_scaffold_034592_01G000300.1; TraesCAD_scaffold_034592_01G000300.1; TraesCAD_scaffold_034592_01G000300.
DR Gramene; TraesCLE_scaffold_034604_01G000300.1; TraesCLE_scaffold_034604_01G000300.1; TraesCLE_scaffold_034604_01G000300.
DR Gramene; TraesPAR_scaffold_030712_01G000300.1; TraesPAR_scaffold_030712_01G000300.1; TraesPAR_scaffold_030712_01G000300.
DR Gramene; TraesROB_scaffold_036448_01G000300.1; TraesROB_scaffold_036448_01G000300.1; TraesROB_scaffold_036448_01G000300.
DR Gramene; TraesWEE_scaffold_093303_01G000100.1; TraesWEE_scaffold_093303_01G000100.1; TraesWEE_scaffold_093303_01G000100.
DR eggNOG; KOG0583; Eukaryota.
DR Proteomes; UP000019116; Unplaced.
DR ExpressionAtlas; Q02066; baseline.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR GO; GO:0006468; P:protein phosphorylation; IBA:GO_Central.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Kinase; Nucleotide-binding; Phosphoprotein;
KW Reference proteome; Serine/threonine-protein kinase; Stress response;
KW Transferase.
FT CHAIN <1..332
FT /note="Abscisic acid-inducible protein kinase"
FT /id="PRO_0000085588"
FT DOMAIN <1..250
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 113
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING <1..8
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 23
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT NON_TER 1
SQ SEQUENCE 332 AA; 37516 MW; E19ACAE1C0F0CE37 CRC64;
GSGNFGVAKL VRDVRTKEHF AVKFIERGHK IDEHVQREIM NHRSLKHPNI IRFKEVVLTP
THLAIVMEYA SGGELFQRIC NAGRFSEDEG RFFFQQLISG VSYCHSMQVC HRDLKLENTL
LDGSVAPRLK ICDFGYSKSS VLHSQPKSTV GTPAYIAPEV LSRREYDGKV ADVWSCGVTL
YVMLVGAYPF EDPDEPRNFR KTITRILSVQ YSVPDYVRVS MDCIHLLSRI FVGNPQQRIT
IPEIKNHPWF LKRLPVEMTD EYQRSMQLAD MNTPSQSLEE AMAIIQEAQK PGDNALGVAG
QVACLGSMDL DDIDFDIDDI DVESSGDFVC PL
