RFA3_ORYSJ
ID RFA3_ORYSJ Reviewed; 106 AA.
AC Q9SDK9; A0A0N7KCP2;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Replication protein A 14 kDa subunit;
DE Short=OsRPA14;
DE AltName: Full=Replication factor A protein 3;
DE AltName: Full=Replication protein A 3;
GN Name=RPA3; Synonyms=RPA14; OrderedLocusNames=Os01g0253600, LOC_Os01g14980;
GN ORFNames=OsJ_01130, P0705D01.4;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH RPA1B AND RPA2A.
RC STRAIN=cv. Nipponbare;
RX PubMed=15978034; DOI=10.1111/j.1742-4658.2005.04719.x;
RA Ishibashi T., Koga A., Yamamoto T., Uchiyama Y., Mori Y., Hashimoto J.,
RA Kimura S., Sakaguchi K.;
RT "Two types of replication protein A in seed plants.";
RL FEBS J. 272:3270-3281(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP INTERACTION WITH RPA2A; RPA2B AND RPA2C.
RX PubMed=16428324; DOI=10.1093/jb/mvj014;
RA Ishibashi T., Kimura S., Sakaguchi K.;
RT "A higher plant has three different types of RPA heterotrimeric complex.";
RL J. Biochem. 139:99-104(2006).
CC -!- FUNCTION: As part of the replication protein A (RPA/RP-A), a single-
CC stranded DNA-binding heterotrimeric complex, may play an essential role
CC in DNA replication, recombination and repair. Binds and stabilizes
CC single-stranded DNA intermediates, preventing complementary DNA
CC reannealing and recruiting different proteins involved in DNA
CC metabolism. {ECO:0000250|UniProtKB:P35244}.
CC -!- SUBUNIT: Component of the heterotrimeric canonical replication protein
CC A complex (RPA) (By similarity). Interacts with RPA1B, RPA2A, RPA2B and
CC RPA2C. {ECO:0000250, ECO:0000269|PubMed:15978034,
CC ECO:0000269|PubMed:16428324}.
CC -!- INTERACTION:
CC Q9SDK9; Q6K9U2: RPA2A; NbExp=5; IntAct=EBI-849521, EBI-849513;
CC Q9SDK9; Q6H7J5: RPA2B; NbExp=2; IntAct=EBI-849521, EBI-849532;
CC Q9SDK9; Q5Z8L1: RPA2C; NbExp=2; IntAct=EBI-849521, EBI-849544;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the replication factor A protein 3 family.
CC {ECO:0000305}.
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DR EMBL; AB111915; BAD06873.1; -; mRNA.
DR EMBL; AP000492; BAA84607.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF04527.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS71369.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ11276.1; -; Genomic_DNA.
DR EMBL; AK058837; BAG86810.1; -; mRNA.
DR RefSeq; XP_015626750.1; XM_015771264.1.
DR RefSeq; XP_015626758.1; XM_015771272.1.
DR AlphaFoldDB; Q9SDK9; -.
DR SMR; Q9SDK9; -.
DR IntAct; Q9SDK9; 3.
DR STRING; 4530.OS01T0253600-01; -.
DR PaxDb; Q9SDK9; -.
DR PRIDE; Q9SDK9; -.
DR EnsemblPlants; Os01t0253600-01; Os01t0253600-01; Os01g0253600.
DR GeneID; 4327706; -.
DR Gramene; Os01t0253600-01; Os01t0253600-01; Os01g0253600.
DR KEGG; osa:4327706; -.
DR eggNOG; ENOG502S57Y; Eukaryota.
DR HOGENOM; CLU_141922_3_0_1; -.
DR InParanoid; Q9SDK9; -.
DR OMA; ANGEYKH; -.
DR OrthoDB; 1594928at2759; -.
DR PlantReactome; R-OSA-9645850; Activation of pre-replication complex.
DR PlantReactome; R-OSA-9675782; Maturation.
DR PlantReactome; R-OSA-9675885; Lagging strand synthesis.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q9SDK9; OS.
DR GO; GO:0031981; C:nuclear lumen; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR013970; Rfa2.
DR Pfam; PF08661; Rep_fac-A_3; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
PE 1: Evidence at protein level;
KW DNA damage; DNA recombination; DNA repair; DNA replication; DNA-binding;
KW Nucleus; Reference proteome.
FT CHAIN 1..106
FT /note="Replication protein A 14 kDa subunit"
FT /id="PRO_0000422628"
SQ SEQUENCE 106 AA; 11365 MW; 24F4A63FFB54A141 CRC64;
MDTSGPAAFV NGEILKMFVG RRVRTVVQAQ REEGGLLIGQ STDGHQLTIK GASGAPMSHY
VEIIGIAEPN QAIRAEVCTD FGENFDPAPF NGLCKLANGQ MKDLFL
