ID   RFAS_ECOLI              Reviewed;         311 AA.
AC   P27126; Q2M7U3;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Lipopolysaccharide core biosynthesis protein RfaS;
GN   Name=rfaS; OrderedLocusNames=b3629, JW3604;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1624461; DOI=10.1128/jb.174.14.4736-4745.1992;
RA   Pradel E., Parker C.T., Schnaitman C.A.;
RT   "Structures of the rfaB, rfaI, rfaJ, and rfaS genes of Escherichia coli K-
RT   12 and their roles in assembly of the lipopolysaccharide core.";
RL   J. Bacteriol. 174:4736-4745(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
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DR   EMBL; M80599; AAA24084.1; -; Genomic_DNA.
DR   EMBL; U00039; AAB18606.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76653.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77663.1; -; Genomic_DNA.
DR   PIR; A42982; A42982.
DR   RefSeq; NP_418086.1; NC_000913.3.
DR   RefSeq; WP_000158225.1; NZ_LN832404.1.
DR   AlphaFoldDB; P27126; -.
DR   SMR; P27126; -.
DR   BioGRID; 4262573; 209.
DR   IntAct; P27126; 3.
DR   STRING; 511145.b3629; -.
DR   jPOST; P27126; -.
DR   PaxDb; P27126; -.
DR   PRIDE; P27126; -.
DR   EnsemblBacteria; AAC76653; AAC76653; b3629.
DR   EnsemblBacteria; BAE77663; BAE77663; BAE77663.
DR   GeneID; 948151; -.
DR   KEGG; ecj:JW3604; -.
DR   KEGG; eco:b3629; -.
DR   PATRIC; fig|1411691.4.peg.3077; -.
DR   EchoBASE; EB1325; -.
DR   eggNOG; COG0438; Bacteria.
DR   eggNOG; COG4641; Bacteria.
DR   HOGENOM; CLU_066435_2_1_6; -.
DR   OMA; WNSEYER; -.
DR   BioCyc; EcoCyc:EG11350-MON; -.
DR   UniPathway; UPA00958; -.
DR   PRO; PR:P27126; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IMP:EcoCyc.
PE   4: Predicted;
KW   Lipopolysaccharide biosynthesis; Reference proteome.
FT   CHAIN           1..311
FT                   /note="Lipopolysaccharide core biosynthesis protein RfaS"
FT                   /id="PRO_0000097287"
SQ   SEQUENCE   311 AA;  36730 MW;  C03F1EBEEA6D5C26 CRC64;
     MTIYFINWVA DYELKMIQYL KKKYKIKNIT TPKKYNWINK KISKIGMDNA WLGRLFIKHY
     LNDIKKDDII IINDSVVNKG INKQILKNIN CHKVLLLRNT VGEDFILDNA NYFDIIYDFE
     HRFIGNEKIK AIEQFFPIGM DEIRNYSLSD KNNSQPICFF LGRDKGRLQI INELAERLTT
     LGCKLDFNVV KDKTSSTTSK YLIEKQISYE ENIRRTLNAN IIVDITKENQ SGWTLRILEA
     LFFNKKLITN NINVFGSEIY SESRFFIIGH DDWDKLEYFI NSSVKPMDYD SLYKFSPDKM
     MSTIVSDFID K