ID   RFAZ_ECOLI              Reviewed;         283 AA.
AC   P27241; Q2M7T8;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Lipopolysaccharide core biosynthesis protein RfaZ;
GN   Name=rfaZ; OrderedLocusNames=b3624, JW3599;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1624462; DOI=10.1128/jb.174.14.4746-4752.1992;
RA   Klena J.D., Pradel E., Schnaitman C.A.;
RT   "Comparison of lipopolysaccharide biosynthesis genes rfaK, rfaL, rfaY, and
RT   rfaZ of Escherichia coli K-12 and Salmonella typhimurium.";
RL   J. Bacteriol. 174:4746-4752(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
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DR   EMBL; M95398; AAA24522.1; -; Genomic_DNA.
DR   EMBL; U00039; AAB18601.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76648.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77668.1; -; Genomic_DNA.
DR   PIR; S47845; S47845.
DR   RefSeq; NP_418081.1; NC_000913.3.
DR   RefSeq; WP_000790279.1; NZ_LN832404.1.
DR   AlphaFoldDB; P27241; -.
DR   BioGRID; 4261610; 243.
DR   IntAct; P27241; 7.
DR   STRING; 511145.b3624; -.
DR   CAZy; GT73; Glycosyltransferase Family 73.
DR   jPOST; P27241; -.
DR   PaxDb; P27241; -.
DR   PRIDE; P27241; -.
DR   EnsemblBacteria; AAC76648; AAC76648; b3624.
DR   EnsemblBacteria; BAE77668; BAE77668; BAE77668.
DR   GeneID; 948146; -.
DR   KEGG; ecj:JW3599; -.
DR   KEGG; eco:b3624; -.
DR   PATRIC; fig|1411691.4.peg.3082; -.
DR   EchoBASE; EB1396; -.
DR   eggNOG; ENOG502Z7NB; Bacteria.
DR   HOGENOM; CLU_090332_0_0_6; -.
DR   OMA; KPFFYVC; -.
DR   PhylomeDB; P27241; -.
DR   BioCyc; EcoCyc:EG11426-MON; -.
DR   BioCyc; MetaCyc:EG11426-MON; -.
DR   UniPathway; UPA00958; -.
DR   PRO; PR:P27241; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IMP:EcoCyc.
DR   InterPro; IPR031026; WaaZ_KDO_III.
DR   TIGRFAMs; TIGR04437; WaaZ_KDO_III; 1.
PE   4: Predicted;
KW   Lipopolysaccharide biosynthesis; Reference proteome.
FT   CHAIN           1..283
FT                   /note="Lipopolysaccharide core biosynthesis protein RfaZ"
FT                   /id="PRO_0000097290"
FT   CONFLICT        58
FT                   /note="S -> G (in Ref. 1; AAA24522)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   283 AA;  32920 MW;  7441DE0DEF192580 CRC64;
     MKNIRYIDKK DVENLIENKI SDDVIIFLSG PTSQKTPLSV LRTKDIIAVN GSAQYLLSNN
     IVPFIYVLTD VRFLHQRRDD FYKFSQRSRY TIVNVDVYEH ASKEDKLYIL QNCLVLRSFY
     RREKGGFIKK IKFNILRQIH KELLISVPLS KKGRLVGFCK DISLGYCSCH TIAFAAIQIA
     YSLKYARIIC SGLDLTGSCS RFYDENKNPM PSELSRDLFK ILPFFRFMHD NVKDINIYNL
     SDDTAISYDV IPFIKLQDIS AEESKDMTRK KMQYRTSTDS YAN