ID   RFBA1_KLEPN             Reviewed;         259 AA.
AC   Q48475;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=O-antigen export system permease protein RfbA;
GN   Name=rfbA;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=O1:K20 / 889/50;
RX   PubMed=7533882; DOI=10.1111/j.1365-2958.1994.tb02185.x;
RA   Bronner D., Clarke B.R., Whitfield C.;
RT   "Identification of an ATP-binding cassette transport system required for
RT   translocation of lipopolysaccharide O-antigen side-chains across the
RT   cytoplasmic membrane of Klebsiella pneumoniae serotype O1.";
RL   Mol. Microbiol. 14:505-519(1994).
CC   -!- FUNCTION: May form an ATP-driven O-antigen export apparatus, in
CC       association with RfbB.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; L31775; AAC98411.1; -; Genomic_DNA.
DR   PIR; S60882; S60882.
DR   AlphaFoldDB; Q48475; -.
DR   SMR; Q48475; -.
DR   TCDB; 3.A.1.103.1; the atp-binding cassette (abc) superfamily.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR000412; ABC_2_transport.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   PROSITE; PS51012; ABC_TM2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Polysaccharide transport;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..259
FT                   /note="O-antigen export system permease protein RfbA"
FT                   /id="PRO_0000182992"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          33..251
FT                   /note="ABC transmembrane type-2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
SQ   SEQUENCE   259 AA;  30036 MW;  074811E58BA5C493 CRC64;
     MSIKMKYNLG YLFDLLVVIT NKDLKVRYKS SMLGYLWSVA NPLLFAMIYY FIFKLVMRVQ
     IPNYTVFLIT GLFPWQWFAS SATNSLFSFI ANAQIIKKTV FPRSVIPLSN VMMEGLHFLC
     TIPVIVVFLF VYGMTPSLSW VWGIPLIAIG QVIFTFGVSI IFSTLNLFFR DLERFVSLGI
     MLMFYCTPIL YASDMIPEKF SWIITYNPLA SMILSWRDLF MNGTLNYEYI SILYFTGIIL
     TVVGLSIFNK LKYRFAEIL