RFBH_SALTY
ID RFBH_SALTY Reviewed; 437 AA.
AC P26398;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Lipopolysaccharide biosynthesis protein RfbH;
GN Name=rfbH; OrderedLocusNames=STM2090;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=1710759; DOI=10.1111/j.1365-2958.1991.tb00741.x;
RA Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
RT "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella
RT serovar typhimurium (strain LT2).";
RL Mol. Microbiol. 5:695-713(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000305};
CC -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC biosynthesis.
CC -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family. {ECO:0000305}.
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DR EMBL; X56793; CAA40122.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20994.1; -; Genomic_DNA.
DR PIR; S15306; S15306.
DR RefSeq; NP_461035.1; NC_003197.2.
DR RefSeq; WP_000126349.1; NC_003197.2.
DR AlphaFoldDB; P26398; -.
DR SMR; P26398; -.
DR STRING; 99287.STM2090; -.
DR PaxDb; P26398; -.
DR EnsemblBacteria; AAL20994; AAL20994; STM2090.
DR GeneID; 1253611; -.
DR KEGG; stm:STM2090; -.
DR PATRIC; fig|99287.12.peg.2212; -.
DR HOGENOM; CLU_033332_5_0_6; -.
DR OMA; GRDCWCP; -.
DR PhylomeDB; P26398; -.
DR BioCyc; SENT99287:STM2090-MON; -.
DR UniPathway; UPA00281; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IBA:GO_Central.
DR GO; GO:0008483; F:transaminase activity; IBA:GO_Central.
DR GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IBA:GO_Central.
DR CDD; cd00616; AHBA_syn; 1.
DR Gene3D; 3.40.640.10; -; 1.
DR Gene3D; 3.90.1150.10; -; 1.
DR InterPro; IPR000653; DegT/StrS_aminotransferase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR30244; PTHR30244; 1.
DR Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR PIRSF; PIRSF000390; PLP_StrS; 1.
DR SUPFAM; SSF53383; SSF53383; 1.
PE 3: Inferred from homology;
KW Lipopolysaccharide biosynthesis; Pyridoxal phosphate; Reference proteome.
FT CHAIN 1..437
FT /note="Lipopolysaccharide biosynthesis protein RfbH"
FT /id="PRO_0000110015"
SQ SEQUENCE 437 AA; 48104 MW; 8EBF7E1164881669 CRC64;
MTANNLREQI SQLVAQYANE ALSPKPFVAG TSVVPPSGKV IGAKELQLMV EASLDGWLTT
GRFNDAFEKK LGEFIGVPHV LTTTSGSSAN LLALTALTSP KLGERALKPG DEVITVAAGF
PTTVNPAIQN GLIPVFVDVD IPTYNIDASL IEAAVTEKSK AIMIAHTLGN AFNLSEVRRI
ADKYNLWLIE DCCDALGTTY EGQMVGTFGD IGTVSFYPAH HITMGEGGAV FTKSGELKKI
IESFRDWGRD CYCAPGCDNT CGKRFGQQLG SLPQGYDHKY TYSHLGYNLK ITDMQAACGL
AQLERVEEFV EQRKANFSYL KQGLQSCTEF LELPEATEKS DPSWFGFPIT LKETSGVNRV
ELVKFLDEAK IGTRLLFAGN LIRQPYFANV KYRVVGELTN TDRIMNQTFW IGIYPGLTTE
HLDYVVSKFE EFFGLNF
