RFBI_SALTY
ID RFBI_SALTY Reviewed; 330 AA.
AC P26395;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Protein RfbI;
GN Name=rfbI; OrderedLocusNames=STM2093;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=1710759; DOI=10.1111/j.1365-2958.1991.tb00741.x;
RA Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
RT "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella
RT serovar typhimurium (strain LT2).";
RL Mol. Microbiol. 5:695-713(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Evidence={ECO:0000305};
CC Note=Binds 1 [2Fe-2S] cluster. {ECO:0000305};
CC -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC biosynthesis.
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DR EMBL; X56793; CAA40119.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20997.1; -; Genomic_DNA.
DR PIR; S15303; S15303.
DR RefSeq; NP_461038.1; NC_003197.2.
DR RefSeq; WP_000018226.1; NC_003197.2.
DR AlphaFoldDB; P26395; -.
DR SMR; P26395; -.
DR STRING; 99287.STM2093; -.
DR PaxDb; P26395; -.
DR DNASU; 1253614; -.
DR EnsemblBacteria; AAL20997; AAL20997; STM2093.
DR GeneID; 1253614; -.
DR KEGG; stm:STM2093; -.
DR PATRIC; fig|99287.12.peg.2215; -.
DR HOGENOM; CLU_003827_7_0_6; -.
DR OMA; IGLPYGC; -.
DR PhylomeDB; P26395; -.
DR BioCyc; SENT99287:STM2093-MON; -.
DR UniPathway; UPA00281; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.40.50.80; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR008333; Cbr1-like_FAD-bd_dom.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR Pfam; PF00970; FAD_binding_6; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; SSF52343; 1.
DR SUPFAM; SSF54292; SSF54292; 1.
DR SUPFAM; SSF63380; SSF63380; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW 2Fe-2S; Iron; Iron-sulfur; Lipopolysaccharide biosynthesis; Metal-binding;
KW Reference proteome.
FT CHAIN 1..330
FT /note="Protein RfbI"
FT /id="PRO_0000189411"
FT DOMAIN 3..89
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00465"
FT DOMAIN 94..192
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
FT BINDING 37
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00465"
FT BINDING 42
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00465"
FT BINDING 45
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00465"
SQ SEQUENCE 330 AA; 36583 MW; EFC1BEC17A0CC82D CRC64;
MSHIIKIFPS NIEFSGREDE SILDAALSAG IHLEHSCKAG DCGICESDLL AGEVVDSKGN
IFGQGDKILT CCCKPKTALE LNAHFFPELA GQTKKIVPCK VNSAVLVSGD VMTLKLRTPP
TAKIGFLPGQ YINLHYKGVT RSYSIANSDE SNGIELHVRN VPNGQMSSLI FGELQENTLM
RIEGPCGTFF IRESDRPIIF LAGGTGFAPV KSMVEHLIQG KCRREIYIYW GMQYSKDFYS
ALPQQWSEQH DNVHYIPVVS GDDAEWGGRK GFVHHAVMDD FDSLEFFDIY ACGSPVMIDA
SKKDFMMKNL SVEHFYSDAF TASNNIEDNL
