ID   RFBX_SALTI              Reviewed;         432 AA.
AC   Q99191;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Putative O-antigen transporter;
GN   Name=rfbX; OrderedLocusNames=STY2297, t0785;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=1856174; DOI=10.1128/jb.173.15.4814-4819.1991;
RA   Liu D., Verma N.K., Romana L.K., Reeves P.R.;
RT   "Relationships among the rfb regions of Salmonella serovars A, B, and D.";
RL   J. Bacteriol. 173:4814-4819(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=8434412; DOI=10.1016/0168-9525(93)90067-r;
RA   Reeves P.R.;
RT   "Evolution of Salmonella O antigen variation by interspecific gene transfer
RT   on a large scale.";
RL   Trends Genet. 9:17-22(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: May be involved in the translocation process of the nascent
CC       O-polysaccharide molecules and/or its ligation to lipid A core units.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
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DR   EMBL; M65054; AAB49394.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD02450.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68476.1; -; Genomic_DNA.
DR   PIR; A42476; A42476.
DR   RefSeq; NP_456636.1; NC_003198.1.
DR   RefSeq; WP_001228890.1; NZ_UCTX01000001.1.
DR   AlphaFoldDB; Q99191; -.
DR   SMR; Q99191; -.
DR   STRING; 220341.16503317; -.
DR   EnsemblBacteria; AAO68476; AAO68476; t0785.
DR   KEGG; stt:t0785; -.
DR   KEGG; sty:STY2297; -.
DR   PATRIC; fig|220341.7.peg.2317; -.
DR   eggNOG; COG2244; Bacteria.
DR   HOGENOM; CLU_052342_0_0_6; -.
DR   OMA; TIICTMI; -.
DR   BioCyc; MetaCyc:MON-21441; -.
DR   UniPathway; UPA00281; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
PE   4: Predicted;
KW   Cell inner membrane; Cell membrane; Lipopolysaccharide biosynthesis;
KW   Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..432
FT                   /note="Putative O-antigen transporter"
FT                   /id="PRO_0000097295"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   432 AA;  48947 MW;  5B566030CC2D8C74 CRC64;
     MRKLRLVRIP RHLIIAASSW LSKIIIAGVQ LVSVKFLLEI LGEESYAVFT LLTGLLVWFS
     IADIGIGSSL QNYISELKAD RKSYDAYIKA AVHILFASLI ILSSTLFFLS DKLSSLYLTS
     FSDELKNNSG SYFFIASILF IFIGVGSVVY KILFAELLGW KANIINALSY LLGFLDVVAI
     HYLMPDSSIT FALVALYAPV AILPIIYISF RYIYVLKAKV NFNTYKLLLS RSSGFLIFSS
     LSIIVLQTDY IVMSQKLSAA DIIKYTVTMK IFGLMFFIYT AVLQALWPVC AELRVKMQWR
     KLHRIIFLNI IGGVFFIGLG TLFIYVLKDY IYSIIANGID YNISGVVFVL LAVYFSIRVW
     CDTFAMLLQS MNQLKILWLI VPCQALIGGV TQWYFAEHYG IVGILYGLIL SFSLTVFWGL
     PVYYMYKSKR LA