ID   RFBX_SALTY              Reviewed;         430 AA.
AC   P26400;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Putative O-antigen transporter;
GN   Name=rfbX; OrderedLocusNames=STM2088;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1710759; DOI=10.1111/j.1365-2958.1991.tb00741.x;
RA   Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
RT   "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella
RT   serovar typhimurium (strain LT2).";
RL   Mol. Microbiol. 5:695-713(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: May be involved in the translocation process of the nascent
CC       O-polysaccharide molecules and/or its ligation to lipid A core units.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
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DR   EMBL; X56793; CAA40124.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20992.1; -; Genomic_DNA.
DR   PIR; S15308; S15308.
DR   RefSeq; NP_461033.1; NC_003197.2.
DR   RefSeq; WP_010989038.1; NC_003197.2.
DR   AlphaFoldDB; P26400; -.
DR   SMR; P26400; -.
DR   STRING; 99287.STM2088; -.
DR   PaxDb; P26400; -.
DR   PRIDE; P26400; -.
DR   EnsemblBacteria; AAL20992; AAL20992; STM2088.
DR   GeneID; 1253609; -.
DR   KEGG; stm:STM2088; -.
DR   PATRIC; fig|99287.12.peg.2210; -.
DR   HOGENOM; CLU_052342_0_0_6; -.
DR   BioCyc; MetaCyc:STM2088-MON; -.
DR   BioCyc; SENT99287:STM2088-MON; -.
DR   UniPathway; UPA00281; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
PE   4: Predicted;
KW   Cell inner membrane; Cell membrane; Lipopolysaccharide biosynthesis;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..430
FT                   /note="Putative O-antigen transporter"
FT                   /id="PRO_0000097296"
FT   TRANSMEM        23..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        342..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        400..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   430 AA;  48628 MW;  328BE52D8362015F CRC64;
     MKVQLLKIPS HLIVAGSSWL SKIIIAGVQL ASISYLISML GEEKYAIFSL LTGLLVWCSA
     VDFGIGTGLQ NYISECRAKN KSYDAYIKSA LHLSFIAIIF FIALFYIFSG VISAKYLSSF
     HEVLQDKTRM LFFTSCLVFS SIGIGAIAYK ILFAELVGWK ANLLNALSYM IGMLGLLYIY
     YRGISVDIKL SLIVLYLPVG MISLCYIVYR YIKLYHVKTT KSHYIAILRR SSGFFLFTLL
     SIVVLQTDYM VISQRLTPAD IVQYTVTMKI FGLVFFIYTA ILQALWPICA ELRVKQQWKK
     LNKMIGVNIL LGSLYVVGCT IFIYLFKEQI FSVIAKDINY QVSILSFMLI GIYFCIRVWC
     DTYAMLLQSM NYLKILWILV PLQAIIGGIA QWYFSSTLGI SGVLLGLIIS FALTVFWGLP
     LTYLIKANKG