ID   RFBX_SHIDY              Reviewed;         396 AA.
AC   Q03583;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Putative O-antigen transporter;
GN   Name=rfbX;
OS   Shigella dysenteriae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=622;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7692219; DOI=10.1111/j.1365-2958.1993.tb01700.x;
RA   Klena J.D., Schnaitman C.A.;
RT   "Function of the rfb gene cluster and the rfe gene in the synthesis of O
RT   antigen by Shigella dysenteriae 1.";
RL   Mol. Microbiol. 9:393-402(1993).
CC   -!- FUNCTION: May be involved in the translocation process of the nascent
CC       O-polysaccharide molecules and/or its ligation to lipid A core units.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000305}.
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DR   EMBL; L07293; AAA16934.1; -; Unassigned_DNA.
DR   PIR; S34963; S34963.
DR   RefSeq; WP_000739384.1; NZ_UAUQ01000007.1.
DR   AlphaFoldDB; Q03583; -.
DR   SMR; Q03583; -.
DR   OMA; RTQYLIP; -.
DR   UniPathway; UPA00281; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002797; Polysacc_synth.
DR   Pfam; PF01943; Polysacc_synt; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Lipopolysaccharide biosynthesis;
KW   Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..396
FT                   /note="Putative O-antigen transporter"
FT                   /id="PRO_0000166450"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   396 AA;  44309 MW;  4C1E506865CDF4BE CRC64;
     MKKNILLLFL VHGANYLFPF IVLPYQTRIL SIETFADVAK IQAAVMLLSL IVNYGYNLSS
     TRAIARAVSQ AEINKIYSET LIVKLLLATI CLALGCVHLM YVKEYSLIYP FIISSIYLYG
     SALFATWLFQ GLEKMKAVVI ATTIAKLTGV ILTFILVKSP NDIVAALFTQ NIGMFISGII
     SIYLVRKNKY ATVICFRLKN IIVSLKEAWP FFLSLAATSV YTYFNVILLS FYAGDYVVAN
     FNAADKLRMA AQGLLIPIGQ AVFPRLSKLE GYEYSSKLKI YAIRYAIFGV CISAGLVFLG
     PMLTTIYLGK EYSLSGEYLQ SMFLLPATIS ISTILSQWML IPQGKEKILS RIYILGAIVH
     LLYAFPLVYY YGAWGMVISI LFTEVLIVLF MLKAVK