ID   RFC3_BLAAD              Reviewed;         338 AA.
AC   O74111;
DT   16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Replication factor C subunit 3;
DE            Short=Replication factor C3;
DE   AltName: Full=Activator 1 subunit 3;
GN   Name=RFC3;
OS   Blastobotrys adeninivorans (Yeast) (Arxula adeninivorans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Trichomonascaceae; Blastobotrys.
OX   NCBI_TaxID=409370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LS3;
RX   PubMed=10022943; DOI=10.1007/s002940050426;
RA   Stoltenburg R., Loesche O., Klappbach G., Kunze G.;
RT   "Molecular cloning and expression of the ARFC3 gene a component of the
RT   replication factor C from the salt tolerant, dimorphic yeast Arxula
RT   adeninivorans LS3.";
RL   Curr. Genet. 35:8-13(1999).
CC   -!- FUNCTION: The elongation of primed DNA templates by DNA polymerase
CC       delta and epsilon requires the action of the accessory proteins
CC       proliferating cell nuclear antigen (PCNA) and activator 1. Subunit 3
CC       binds ATP (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heteropentamer of subunits RFC1, RFC2, RFC3, RFC4 and RFC5
CC       that forms a complex with PCNA in the presence of ATP. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC       {ECO:0000305}.
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DR   EMBL; AJ007712; CAA07618.1; -; Genomic_DNA.
DR   AlphaFoldDB; O74111; -.
DR   SMR; O74111; -.
DR   PhylomeDB; O74111; -.
DR   GO; GO:0031391; C:Elg1 RFC-like complex; IEA:UniProt.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0090618; P:DNA clamp unloading; IEA:UniProt.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013748; Rep_factorC_C.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF08542; Rep_fac_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA replication; Nucleotide-binding; Nucleus.
FT   CHAIN           1..338
FT                   /note="Replication factor C subunit 3"
FT                   /id="PRO_0000121754"
FT   BINDING         57..64
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   338 AA;  37640 MW;  40BC3F5A97D27C63 CRC64;
     MDKGKKVETV EKQENSLPWV EKYRPTTLDE VAGHEGVITT IKKFVEEGKL PHLLFHGPPG
     TGKTTTIIAV ARQIYGKNYR NMILELNASD ERGIDVVRDQ IKTFASTRQI FSSGFKLVIL
     DEADAMTNAA QNALRRIIEK YSAHTRFCIL ANYTHKLNPA LLSRCTRFRF SPLKEDAIKH
     RLAHVIEQES VDLSPEAFQS LLHLSSGDMR RALNVLQACY ASVDAGEQIS EELVYDCVGS
     PRPADIRTVL QAVLDGSWES ALHTFSYIKQ SKGLALADML TAFAVEFQKL DLQNKTRIAL
     LDGLSEIEWR LSSGGNESIQ TSATIGVIKQ SMELEASS