ID   RFC3_ORYSJ              Reviewed;         361 AA.
AC   Q6YZ54; A0A0N7KG66; Q9FXT5;
DT   26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Replication factor C subunit 3;
DE            Short=OsRFC3;
DE   AltName: Full=Activator 1 subunit 3;
GN   Name=RFC3; OrderedLocusNames=Os02g0775200, LOC_Os02g53500;
GN   ORFNames=OJ1448_G06.20, OSJNBb0013K01.1;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INDUCTION.
RC   STRAIN=cv. Nipponbare;
RA   Furukawa T., Kimura S., Ishibashi T., Hashimoto J., Sakaguchi K.;
RT   "A plant homologue of 36 kDa subunit of replication factor C: molecular
RT   cloning and characterization.";
RL   Plant Sci. 161:99-106(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   TISSUE SPECIFICITY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=14756303; DOI=10.1023/b:plan.0000009258.04711.62;
RA   Furukawa T., Ishibashi T., Kimura S., Tanaka H., Hashimoto J.,
RA   Sakaguchi K.;
RT   "Characterization of all the subunits of replication factor C from a higher
RT   plant, rice (Oryza sativa L.), and their relation to development.";
RL   Plant Mol. Biol. 53:15-25(2003).
CC   -!- FUNCTION: May be involved in DNA replication and thus regulate cell
CC       proliferation. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can
CC       form a complex with RFC1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, leaves, shoot apical meristem
CC       (SAM), flag leaves and panicles. {ECO:0000269|PubMed:14756303,
CC       ECO:0000269|Ref.1}.
CC   -!- INDUCTION: Down-regulated by sucrose starvation. {ECO:0000269|Ref.1}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB16439.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR   EMBL; AB038319; BAB16439.1; ALT_SEQ; mRNA.
DR   EMBL; AP004853; BAD17147.1; -; Genomic_DNA.
DR   EMBL; AP005538; BAD17365.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF10194.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS81161.1; -; Genomic_DNA.
DR   EMBL; AK069984; BAG91711.1; -; mRNA.
DR   RefSeq; XP_015627208.1; XM_015771722.1.
DR   AlphaFoldDB; Q6YZ54; -.
DR   SMR; Q6YZ54; -.
DR   STRING; 4530.OS02T0775200-01; -.
DR   PaxDb; Q6YZ54; -.
DR   PRIDE; Q6YZ54; -.
DR   EnsemblPlants; Os02t0775200-01; Os02t0775200-01; Os02g0775200.
DR   GeneID; 4330895; -.
DR   Gramene; Os02t0775200-01; Os02t0775200-01; Os02g0775200.
DR   KEGG; osa:4330895; -.
DR   eggNOG; KOG0990; Eukaryota.
DR   HOGENOM; CLU_042324_2_1_1; -.
DR   InParanoid; Q6YZ54; -.
DR   OMA; TRTIFCG; -.
DR   OrthoDB; 1071197at2759; -.
DR   PlantReactome; R-OSA-9675815; Leading strand synthesis.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6YZ54; OS.
DR   GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   GO; GO:0031348; P:negative regulation of defense response; IEA:EnsemblPlants.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013748; Rep_factorC_C.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF08542; Rep_fac_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; DNA replication; Nucleotide-binding; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..361
FT                   /note="Replication factor C subunit 3"
FT                   /id="PRO_0000422636"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         77..84
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   361 AA;  39626 MW;  443998FC45F80199 CRC64;
     MAGATAATPM DIDAAAPPPG AAAKGKAPLS STPGGRAAPW VEKYRPQSLG DVAAHRDIVD
     TIDRLTNENR LPHLLLYGPP GTGKTSTILA VARKLYGSQY GNMILELNAS DERGIDVVRQ
     QIQDFASARS LSFGAKQSVK MVLLDEADAM TKDAQFALRR VIEKHTRSTR FALICNHVNK
     IIPALQSRCT RFRFAPLDGT HVRERLKHII QSEGLDVDDG GLTALVRLSN GDMRKALNIL
     QSTHMASKQI TEEAVYLCTG NPMPKDIEQI AYWLLNESFS TSFKCISDMK MRKGLALVDI
     IREVTMFVFK IQMPSDVRIK LINDLADIEY RLSFACNDKL QLGALISTFT GARTAMVAAA
     H