RFC5_ORYSJ
ID RFC5_ORYSJ Reviewed; 354 AA.
AC Q852K3; A0A0P0W4P5; Q84N07;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Replication factor C subunit 5;
DE Short=OsRFC5;
DE AltName: Full=Activator 1 subunit 5;
GN Name=RFC5; OrderedLocusNames=Os03g0792600, LOC_Os03g57870;
GN ORFNames=OsJ_12910, OSJNBb0060J21.20;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INDUCTION, AND GENE FAMILY.
RC STRAIN=cv. Nipponbare;
RX PubMed=14756303; DOI=10.1023/b:plan.0000009258.04711.62;
RA Furukawa T., Ishibashi T., Kimura S., Tanaka H., Hashimoto J.,
RA Sakaguchi K.;
RT "Characterization of all the subunits of replication factor C from a higher
RT plant, rice (Oryza sativa L.), and their relation to development.";
RL Plant Mol. Biol. 53:15-25(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: May be involved in DNA replication and thus regulate cell
CC proliferation. {ECO:0000250}.
CC -!- SUBUNIT: Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can
CC form a complex with RFC1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, shoot apical meristem
CC (SAM), flag leaves and panicles. {ECO:0000269|PubMed:14756303}.
CC -!- INDUCTION: Down-regulated by sucrose starvation.
CC {ECO:0000269|PubMed:14756303}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000305}.
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DR EMBL; AB109201; BAC76086.1; -; mRNA.
DR EMBL; AC090871; AAO37979.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF99302.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF13439.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS86798.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE60080.1; -; Genomic_DNA.
DR EMBL; AK059559; BAG87033.1; -; mRNA.
DR EMBL; AK103751; BAG96243.1; -; mRNA.
DR RefSeq; XP_015630600.1; XM_015775114.1.
DR AlphaFoldDB; Q852K3; -.
DR SMR; Q852K3; -.
DR STRING; 4530.OS03T0792600-01; -.
DR PaxDb; Q852K3; -.
DR PRIDE; Q852K3; -.
DR EnsemblPlants; Os03t0792600-01; Os03t0792600-01; Os03g0792600.
DR EnsemblPlants; Os03t0792600-02; Os03t0792600-02; Os03g0792600.
DR GeneID; 4334389; -.
DR Gramene; Os03t0792600-01; Os03t0792600-01; Os03g0792600.
DR Gramene; Os03t0792600-02; Os03t0792600-02; Os03g0792600.
DR KEGG; osa:4334389; -.
DR eggNOG; KOG2035; Eukaryota.
DR HOGENOM; CLU_042324_5_0_1; -.
DR InParanoid; Q852K3; -.
DR OMA; LMCEACK; -.
DR OrthoDB; 1071197at2759; -.
DR PlantReactome; R-OSA-9675815; Leading strand synthesis.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q852K3; OS.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; DNA replication; Nucleotide-binding; Nucleus;
KW Reference proteome.
FT CHAIN 1..354
FT /note="Replication factor C subunit 5"
FT /id="PRO_0000422638"
FT BINDING 40..47
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT CONFLICT 125
FT /note="A -> V (in Ref. 1; BAC76086)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 354 AA; 40524 MW; 514B3B5A341941EA CRC64;
MLWVDKYRPK TLDKVTVHDQ VAQNLKKLVA EQDCPHLLFY GPSGSGKKTL VMALIKQMFG
AGADKVKMEN KTWKIDTGSR NIEIELAMLS SAHHVEMNPS DAGFQDRYVV QEVIKEMAKN
RPIDAKGKRA FKVLVLNEVD KLSREAQHSL RRTMEKYSAS CRLILCCNSS SKVTEAVRSR
CLNVRVNAPS EDQIVQVLEF IGKKENLQLP FGFAARIAAQ SNRNLRRAIL FFETCKVQQY
PFTSNQVAPP LDWEQYVSEI AADIMKEQSP KRLFAVRQKF YELLVNCIPP ESILKKLLAE
LLKKLDSDLK HEICHWAAHY EHKMRLGSKA IFHLEAFVAK FMSIYKEFLV STFG
