ID   RFCL_MIMIV              Reviewed;         533 AA.
AC   Q5UQK9;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   23-FEB-2022, entry version 67.
DE   RecName: Full=Putative replication factor C large subunit;
DE            Short=RFC large subunit;
DE   AltName: Full=Clamp loader large subunit;
GN   OrderedLocusNames=MIMI_R411;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC       sliding clamp onto DNA. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AY653733; AAV50680.1; -; Genomic_DNA.
DR   RefSeq; YP_003986915.1; NC_014649.1.
DR   SMR; Q5UQK9; -.
DR   GeneID; 9925032; -.
DR   KEGG; vg:9925032; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF08519; RFC1; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   DNA replication; Reference proteome.
FT   CHAIN           1..533
FT                   /note="Putative replication factor C large subunit"
FT                   /id="PRO_0000309209"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..31
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   533 AA;  61391 MW;  4B52FB1F947D913A CRC64;
     MSKTAKNTKT IKSVKSVNKD NKPNKDNKDD KNVDEEVINW LDKYKPTSSS QILGDKNNIN
     RIKAFLSQFT KENAEINCPN LILTGNNGVG KTLMTDLIIQ EKGFEKITAD LTNISVARKS
     KKKKKVEKEY NGSNRTIKTY YTTLYNKSVS PTGDLIEKKI VVVFDDVSNI SNNKEKEAIK
     SIIKINSKEK KIPIIIIANM KHSKTVNELK KMVTVTVKNT NSQGRKENKR TSNEIIIKAP
     NPDEIREFIA YICRKENLKL KQRKSDDDDI YEEIIQHSQF DIRRLIYILE SLKMIHGNND
     VTLDEFDAYR EISKTKDIDP GIYKATGTLL NDYEGISGAL SLYEEERATI PLMVHENYPS
     NIKHQYPKMS VEDQISVIHK ISESISESDK IDGLIYSNQC WSLQPVHGFY SCVLPSYFIN
     MHPNKLRMSE IYKYTQDYNK TSIKKINNKV IKKAQENQHL KRVSIYDFLY MASILKTLLE
     RKDFEAVATL MKPYGLKLKE IESIIKIDKI KKMKNTLTGK QKTQLKELLG VDE