ID   RFCL_SULIY              Reviewed;         405 AA.
AC   C3NE95;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Replication factor C large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
DE            Short=RFC large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
DE   AltName: Full=Clamp loader large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
GN   Name=rfcL {ECO:0000255|HAMAP-Rule:MF_01508}; OrderedLocusNames=YG5714_1367;
OS   Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=439386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y.G.57.14 / Yellowstone #1;
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC       sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01508}.
CC   -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC       subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01508}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcL
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01508}.
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DR   EMBL; CP001403; ACP45634.1; -; Genomic_DNA.
DR   RefSeq; WP_012713707.1; NC_012622.1.
DR   AlphaFoldDB; C3NE95; -.
DR   SMR; C3NE95; -.
DR   EnsemblBacteria; ACP45634; ACP45634; YG5714_1367.
DR   GeneID; 7806753; -.
DR   GeneID; 8761317; -.
DR   KEGG; siy:YG5714_1367; -.
DR   HOGENOM; CLU_027255_1_1_2; -.
DR   OMA; GGWTRYG; -.
DR   Proteomes; UP000002308; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01508; RfcL; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR023935; Rep_factor-C_lsu.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding.
FT   CHAIN           1..405
FT                   /note="Replication factor C large subunit"
FT                   /id="PRO_1000215344"
FT   BINDING         47..54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01508"
SQ   SEQUENCE   405 AA;  46627 MW;  ED11FF712E5B9A79 CRC64;
     MIQWFLKYRP RSLKDVENQD GAKKELQEWI ESWLNGKPNA KAVLLHGPPG VGKTTLAEAL
     AHDYNLELLE MNASDSRKLQ DIKGVAEKAS VYGSIFGTRG KLILLDEVDG INVREDTGAI
     QGILELIEKT KYPIIMTAND PWNPALRELR NKTKMVGLNK LGKYPLRRLL KKICQAEKII
     CDDEALNYII DTSEGDARYA INMLQGIGEG YGKVTLDLVE AMARRKEREL DPFETLRDIF
     WARYAWQAKN AATSAQIDYD MLIRWISENI PIQYDNIEDV WRAFDALSRA SIFLKRAKGG
     DWDLLSYAYD LMSSGVAAAE IEKKKPNWKP KWKKYQFPSY IQLLSKSKDI RDTRDEIIKK
     LAIHSSFNKT LNDTYPFFLI FYKKYDKRLS LNTKEKEYLN SASKS