ID   RFCL_SULTO              Reviewed;         440 AA.
AC   Q975D4; F9VMZ9;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-FEB-2004, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Replication factor C large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
DE            Short=RFC large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
DE   AltName: Full=Clamp loader large subunit {ECO:0000255|HAMAP-Rule:MF_01508};
GN   Name=rfcL {ECO:0000255|HAMAP-Rule:MF_01508}; OrderedLocusNames=STK_04730;
OS   Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS   (Sulfolobus tokodaii).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfurisphaera.
OX   NCBI_TaxID=273063;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX   PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA   Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA   Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA   Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA   Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT   "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT   Sulfolobus tokodaii strain7.";
RL   DNA Res. 8:123-140(2001).
CC   -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC       sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01508}.
CC   -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC       subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01508}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcL
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01508}.
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DR   EMBL; BA000023; BAK54296.1; -; Genomic_DNA.
DR   RefSeq; WP_052846342.1; NC_003106.2.
DR   AlphaFoldDB; Q975D4; -.
DR   SMR; Q975D4; -.
DR   STRING; 273063.STK_04730; -.
DR   EnsemblBacteria; BAK54296; BAK54296; STK_04730.
DR   GeneID; 1458416; -.
DR   KEGG; sto:STK_04730; -.
DR   PATRIC; fig|273063.9.peg.548; -.
DR   eggNOG; arCOG00470; Archaea.
DR   OMA; GGWTRYG; -.
DR   OrthoDB; 24257at2157; -.
DR   Proteomes; UP000001015; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01508; RfcL; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR023935; Rep_factor-C_lsu.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Replication factor C large subunit"
FT                   /id="PRO_0000135967"
FT   BINDING         48..55
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01508"
SQ   SEQUENCE   440 AA;  51116 MW;  98E80D335C2CA562 CRC64;
     MPLQWFLKYR PKTLNEVENE EDAKKELVEW IESWLKGKPN YKAVLLYGPP GVGKTTLAEA
     LARDYKLELF EMNASDSRNL NDIRTMAERA SITGTIFGIK GKLILLDEVD GLNARADAGA
     IDAILELINK TKYPIILTAN DPWDPSLRPL RNAVKMIELK RLTKYPLKRI LKKICEAEKI
     TCEDEALDFI IEQSEGDARY AINMLQGVAE GYGRVTLDMA KNLVRRKDRE LDPFEALRGV
     FWAKYYWQAK SAVTDTQIDY ELLMRWLDEN IPLQYDNLED VWRAYDALSR ASLFLTRSKL
     VGWDLLSYTF DLMGPGIAFA SLEKKKPTYK AKWVKYQFPQ YIQQLAKTKE IRDALDTLLR
     KIGQAIHASK DKTLNDFLPA FIIYYRKYQE KLDKELELTE KEKDVIKLIS SFYEGSKVEI
     EEPEKKEPSK RRTTSYRRKS