ID   RFCS1_PYRAE             Reviewed;         329 AA.
AC   Q8ZYK4;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Replication factor C small subunit 1 {ECO:0000255|HAMAP-Rule:MF_01509};
DE            Short=RFC small subunit 1 {ECO:0000255|HAMAP-Rule:MF_01509};
DE   AltName: Full=Clamp loader small subunit 1 {ECO:0000255|HAMAP-Rule:MF_01509};
GN   Name=rfcS1 {ECO:0000255|HAMAP-Rule:MF_01509}; OrderedLocusNames=PAE0734;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC       sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC   -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC       subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01509}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcS
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE009441; AAL62989.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZYK4; -.
DR   SMR; Q8ZYK4; -.
DR   STRING; 178306.PAE0734; -.
DR   PRIDE; Q8ZYK4; -.
DR   EnsemblBacteria; AAL62989; AAL62989; PAE0734.
DR   KEGG; pai:PAE0734; -.
DR   PATRIC; fig|178306.9.peg.534; -.
DR   eggNOG; arCOG00469; Archaea.
DR   HOGENOM; CLU_042324_2_1_2; -.
DR   InParanoid; Q8ZYK4; -.
DR   OMA; SCNYSSQ; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01509; RfcS; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR023748; Rep_factor-C_ssu_arc.
DR   InterPro; IPR013748; Rep_factorC_C.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF08542; Rep_fac_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..329
FT                   /note="Replication factor C small subunit 1"
FT                   /id="PRO_0000135981"
FT   BINDING         44..51
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01509"
SQ   SEQUENCE   329 AA;  37392 MW;  5474BD7FBE52FB0D CRC64;
     MAELFWFEKY RPRSFDEVVD LEEVKARLRE FVKAGNMPHL LFYGPPGTGK TTMALVLARE
     LYGEYWRENT LELNASDERG INVIRERVKE FARTAPVGKA PFKLVILDEA DNMTSDAQQA
     LRRIMEIYAQ NTRFILLANY VSRIIDPIIS RCAVFRFSPM PRSLMAERLK FIAKNEGVEL
     REDAINMIYE LSEGDMRKAI NLLQVAAATN KVVDANAVAS AAIAVRPADI IELFNLAISG
     DFVKAREKLR ELMYLKGIAG ADFIRAFQRE LIRMPIDDDI KAEIAELLAD VDYRLTQGAD
     EEIQLTYLLT KLGAIGRRVK PATTQPRKK