RFCS_HALMA
ID RFCS_HALMA Reviewed; 325 AA.
AC Q5UZE5;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 2.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Replication factor C small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE Short=RFC small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE AltName: Full=Clamp loader small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
GN Name=rfcS {ECO:0000255|HAMAP-Rule:MF_01509}; Synonyms=rfcC1;
GN OrderedLocusNames=rrnAC2565;
OS Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS B-1809) (Halobacterium marismortui).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=272569;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX PubMed=15520287; DOI=10.1101/gr.2700304;
RA Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA Hood L., Ng W.V.;
RT "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT Dead Sea.";
RL Genome Res. 14:2221-2234(2004).
CC -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcS
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAV47358.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AY596297; AAV47358.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_049939018.1; NZ_CP039138.1.
DR AlphaFoldDB; Q5UZE5; -.
DR SMR; Q5UZE5; -.
DR STRING; 272569.rrnAC2565; -.
DR EnsemblBacteria; AAV47358; AAV47358; rrnAC2565.
DR GeneID; 40153450; -.
DR KEGG; hma:rrnAC2565; -.
DR PATRIC; fig|272569.17.peg.3165; -.
DR eggNOG; arCOG00469; Archaea.
DR HOGENOM; CLU_042324_2_1_2; -.
DR Proteomes; UP000001169; Chromosome I.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01509; RfcS; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR023748; Rep_factor-C_ssu_arc.
DR InterPro; IPR013748; Rep_factorC_C.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT CHAIN 1..325
FT /note="Replication factor C small subunit"
FT /id="PRO_0000135972"
FT BINDING 54..61
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01509"
SQ SEQUENCE 325 AA; 36067 MW; 28247C6EBD804A88 CRC64;
MSEAESESRA GREEVWIEKY RPQTLDDVMG HENIVGRLKS YVSRNDLSHM LFSGPAGTGK
TTCATAIARE LYGDDWREHF LELNASDERG IDVVRDRIKN FARTSFGGVE YRIIFLDEAD
ALTSDAQSAL RRTMEQFSNN VRFILSCNYS SQIIDPIQSR CAVFRFSPLA DDAVAEEIRT
IAAEEDIELT EDGLDALVYA ADGDMRKAIN GLQAASVSGD TVDESAVYAI TSTARPEEIR
TMVQSALDGD FTASRATLDR LLTEEGIAGG DIIDQLHRSI WEFDIDDDAA VRVLERIGET
DYRITRGANE RVQLEAMLAS LAQGE
