ID   RFCS_HALWD              Reviewed;         649 AA.
AC   Q18E75;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Replication factor C small subunit;
DE            Short=RFC small subunit;
DE   AltName: Full=Clamp loader small subunit;
DE   Contains:
DE     RecName: Full=Hwa RFC intein;
GN   Name=rfcS; OrderedLocusNames=HQ_3671A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC       sliding clamp onto DNA. {ECO:0000250}.
CC   -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC       subunits (RfcL). {ECO:0000250}.
CC   -!- PTM: This protein undergoes a protein self splicing that involves a
CC       post-translational excision of the intervening region (intein) followed
CC       by peptide ligation. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcS
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AM180088; CAJ53758.1; -; Genomic_DNA.
DR   RefSeq; WP_011572840.1; NC_008212.1.
DR   AlphaFoldDB; Q18E75; -.
DR   SMR; Q18E75; -.
DR   STRING; 362976.HQ_3671A; -.
DR   EnsemblBacteria; CAJ53758; CAJ53758; HQ_3671A.
DR   GeneID; 4194575; -.
DR   KEGG; hwa:HQ_3671A; -.
DR   eggNOG; arCOG00469; Archaea.
DR   eggNOG; arCOG03146; Archaea.
DR   HOGENOM; CLU_015698_2_1_2; -.
DR   OMA; QFADNTR; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR003587; Hint_dom_N.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR006142; INTEIN.
DR   InterPro; IPR030934; Intein_C.
DR   InterPro; IPR006141; Intein_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013748; Rep_factorC_C.
DR   Pfam; PF08542; Rep_fac_C; 1.
DR   PRINTS; PR00379; INTEIN.
DR   SMART; SM00306; HintN; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF51294; SSF51294; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR01445; intein_Nterm; 1.
DR   PROSITE; PS50818; INTEIN_C_TER; 1.
DR   PROSITE; PS50817; INTEIN_N_TER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Autocatalytic cleavage; DNA replication; Nucleotide-binding;
KW   Protein splicing; Reference proteome.
FT   CHAIN           1..61
FT                   /note="Replication factor C small subunit, 1st part"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000296647"
FT   CHAIN           62..384
FT                   /note="Hwa RFC intein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000296648"
FT   CHAIN           385..649
FT                   /note="Replication factor C small subunit, 2nd part"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000296649"
FT   BINDING         55..385
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   649 AA;  70442 MW;  7FB7838FA03877CC CRC64;
     MSEADASDAA PTGREIWIEK YRPATLENIY GQEDTVDRLQ SYIDRDDLPH LLFAGPAGVG
     KCVTGSTPIL TNKGIRQIGE IVGDVDGFAP APQNLKVCSL TADGSFQYRH PSHVFGKRAS
     GLQRIKTNDG ATLTVTPEHK LLIRTGENTN PTWVPAADIT AGMHVLRAKN LPIPAETTGS
     CAASKNASEV SHIGDEYRYH DSLMADVNTR IATLERLIED YAESRSDGSL KFTLIGAHTP
     TVSTVSYLLA TVGIASRHTS TLIDSEKRVH AIIIDASDTV RLEEMIETDW DTVMADQTTT
     VTSSSTASTT KTTQSYLSSG ETQTCGWIPY ADGGVTHPST QHSPLHADVV TVSESLDAEK
     RVYDLTVPGV RNYVGGCIPT VMHNTTAATA IAHAVYGDDW QNNLLELNAS DERGIDVVRD
     RIKNFARSSF GGYDHRIIFL DEADSLTDDA QSALRRTMEQ FADNTRFILS CNYSSKIIDP
     IQSRCAVFRF SPLSETAIRG QTKDIAAAEN IELTEDGLDA LVYAAGGDMR RAINSLQAAA
     TTGEVVDEET VYTITSTARP EDIETMVTAA IDGDFTTARS QLQTLLVDTG MAGGDIIDQL
     HRTAWNLDLD EETTVRLLER VGEADYRITV GANEQVQLEA LLASLADTQ