RFCS_NATPD
ID RFCS_NATPD Reviewed; 325 AA.
AC Q3ITJ2;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Replication factor C small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE Short=RFC small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE AltName: Full=Clamp loader small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
GN Name=rfcS {ECO:0000255|HAMAP-Rule:MF_01509}; Synonyms=rfcA;
GN OrderedLocusNames=NP_0900A;
OS Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS 8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Natronomonas.
OX NCBI_TaxID=348780;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB
RC 2260 / Gabara;
RX PubMed=16169924; DOI=10.1101/gr.3952905;
RA Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA Oesterhelt D.;
RT "Living with two extremes: conclusions from the genome sequence of
RT Natronomonas pharaonis.";
RL Genome Res. 15:1336-1343(2005).
CC -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcS
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01509}.
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DR EMBL; CR936257; CAI48541.1; -; Genomic_DNA.
DR RefSeq; WP_011322177.1; NC_007426.1.
DR AlphaFoldDB; Q3ITJ2; -.
DR SMR; Q3ITJ2; -.
DR STRING; 348780.NP_0900A; -.
DR EnsemblBacteria; CAI48541; CAI48541; NP_0900A.
DR GeneID; 3703100; -.
DR KEGG; nph:NP_0900A; -.
DR eggNOG; arCOG00469; Archaea.
DR HOGENOM; CLU_042324_2_1_2; -.
DR OMA; SCNYSSQ; -.
DR OrthoDB; 37207at2157; -.
DR Proteomes; UP000002698; Chromosome.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01509; RfcS; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR023748; Rep_factor-C_ssu_arc.
DR InterPro; IPR013748; Rep_factorC_C.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT CHAIN 1..325
FT /note="Replication factor C small subunit"
FT /id="PRO_0000135979"
FT BINDING 52..59
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01509"
SQ SEQUENCE 325 AA; 35722 MW; C81EAC71206F1851 CRC64;
MSEGDADGGG REIWIEKYRP QTLDDIVGHE SITERLKQYI AQNDLPHLLF AGPAGVGKTT
AATAIAKEVY GDDWRENFLE LNASDQRGID VVRDRIKSFA RASFGGYDHR IIFLDEADAL
TSDAQSALRR TMEQFSDNTR FILSCNYSSQ IIDPIQSRCA VFRFSPLGDA AVDEQIRIIA
DTEGIELTDD GVDALVYAAD GDMRKAINGL QAAAVMGGTV DEEAVYTITS TARPEEIREM
VTEAMDGDFT AARSQLETLL TDVGIAGGDI IDQLHRSVWE FDLEEREAVQ LMERIGEADY
RITAGASEQL QLEALLAALA RGNET
