RFCS_THEVO
ID RFCS_THEVO Reviewed; 318 AA.
AC Q977Z9;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 2.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Replication factor C small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE Short=RFC small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
DE AltName: Full=Clamp loader small subunit {ECO:0000255|HAMAP-Rule:MF_01509};
GN Name=rfcS {ECO:0000255|HAMAP-Rule:MF_01509}; OrderedLocusNames=TV1518;
GN ORFNames=TVG1570739;
OS Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS 15438 / GSS1).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC Thermoplasmataceae; Thermoplasma.
OX NCBI_TaxID=273116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT Thermoplasma volcanium.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC -!- FUNCTION: Part of the RFC clamp loader complex which loads the PCNA
CC sliding clamp onto DNA. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SUBUNIT: Heteromultimer composed of small subunits (RfcS) and large
CC subunits (RfcL). {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family. RfcS
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01509}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB60660.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BA000011; BAB60660.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_010917747.1; NC_002689.2.
DR AlphaFoldDB; Q977Z9; -.
DR SMR; Q977Z9; -.
DR STRING; 273116.14325757; -.
DR EnsemblBacteria; BAB60660; BAB60660; BAB60660.
DR GeneID; 1442207; -.
DR KEGG; tvo:TVG1570739; -.
DR eggNOG; arCOG00469; Archaea.
DR HOGENOM; CLU_042324_2_1_2; -.
DR OMA; SCNYSSQ; -.
DR OrthoDB; 37207at2157; -.
DR PhylomeDB; Q977Z9; -.
DR Proteomes; UP000001017; Chromosome.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01509; RfcS; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR023748; Rep_factor-C_ssu_arc.
DR InterPro; IPR013748; Rep_factorC_C.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding.
FT CHAIN 1..318
FT /note="Replication factor C small subunit"
FT /id="PRO_0000135987"
FT BINDING 43..50
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01509"
SQ SEQUENCE 318 AA; 35666 MW; 41BE7007C87E0884 CRC64;
MIEIWTEKYR PKSLSEIYGE DENIQKLKSF VEKKELPHLL FAGSVGTGKT STAIALAIEL
FGESWKENFI EMNASNENGI DVIRNKIKDI ARIRPSNPLG FKILFLDEAD QLTAEAQAAL
RRTMEMYSET TRFVFACNYS SKIIPPIQSR TVVMRFRPVQ DEFIKKKLNE IAKNEGFTID
DESMEAMVEV SGGDMRKAIN VLQAVYTSGE ISPKKIYEII GYASPESVNK LISRAINGLF
DEARQIVDKM MIEDGLSGID IVKSVHSIVR ASVVPPKQKI EIIKALADAE FRIVEGSNDR
IQLDALIARI ADIGSKIN
