ID   RFRNP_HALHL             Reviewed;         206 AA.
AC   A1WZ95;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=RNA-free ribonuclease P {ECO:0000255|HAMAP-Rule:MF_01078};
DE            Short=RNA-free RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
DE            EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_01078};
DE   AltName: Full=Protein-only RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
GN   OrderedLocusNames=Hhal_2243;
OS   Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira
OS   halophila (strain DSM 244 / SL1)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Halorhodospira.
OX   NCBI_TaxID=349124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 244 / SL1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W.,
RA   Richardson P.;
RT   "Complete sequence of Halorhodospira halophila SL1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA-free RNase P that catalyzes the removal of the 5'-leader
CC       sequence from pre-tRNA to produce the mature 5'-terminus.
CC       {ECO:0000255|HAMAP-Rule:MF_01078}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01078};
CC   -!- SIMILARITY: Belongs to the HARP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01078}.
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DR   EMBL; CP000544; ABM63007.1; -; Genomic_DNA.
DR   RefSeq; WP_011815029.1; NC_008789.1.
DR   PDB; 7OG5; EM; 3.37 A; A/B/C/D/E/F/G/H/I/J/K/L=2-206.
DR   PDBsum; 7OG5; -.
DR   AlphaFoldDB; A1WZ95; -.
DR   SMR; A1WZ95; -.
DR   STRING; 349124.Hhal_2243; -.
DR   EnsemblBacteria; ABM63007; ABM63007; Hhal_2243.
DR   KEGG; hha:Hhal_2243; -.
DR   eggNOG; COG1458; Bacteria.
DR   HOGENOM; CLU_109672_0_0_6; -.
DR   OMA; YIIKKPP; -.
DR   OrthoDB; 1359470at2; -.
DR   Proteomes; UP000000647; Chromosome.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01078; RNA_free_RNase_P; 1.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR014856; RNA_free_RNase_P.
DR   PANTHER; PTHR41173; PTHR41173; 1.
DR   Pfam; PF08745; PIN_5; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
DR   TIGRFAMs; TIGR03875; RNA_lig_partner; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Endonuclease; Hydrolase; Nuclease; Reference proteome;
KW   tRNA processing.
FT   CHAIN           1..206
FT                   /note="RNA-free ribonuclease P"
FT                   /id="PRO_0000366686"
FT   REGION          187..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   HELIX           8..11
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   TURN            14..16
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   TURN            18..20
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           24..34
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   TURN            35..37
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   STRAND          42..44
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           46..55
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           59..68
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   STRAND          69..71
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           83..95
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           126..130
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           133..153
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           162..171
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           178..180
FT                   /evidence="ECO:0007829|PDB:7OG5"
FT   HELIX           181..185
FT                   /evidence="ECO:0007829|PDB:7OG5"
SQ   SEQUENCE   206 AA;  23583 MW;  745BD291C39D6079 CRC64;
     MRRFVLDTSV FTNPDVYLRF DEEPMQAISV FLGLARRADA EFYMPGPVYQ ELCNLRSMDL
     IGAEFETEVY IRSPRRFSMT IPSEVLYEFI EEVRTRIQRG LRIAEEHARQ AGQAESLPPE
     LITQLRERYR EAMRRGILDS REDIDVVLLA YELDATLVSA DEGMRKFAER IGIKLVNPRY
     LRGVMQNLAG DDPGHAPPCG PDQPAG