RFRNP_HYPBU
ID RFRNP_HYPBU Reviewed; 238 AA.
AC A2BN08;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=RNA-free ribonuclease P {ECO:0000255|HAMAP-Rule:MF_01078};
DE Short=RNA-free RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
DE EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_01078};
DE AltName: Full=Protein-only RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
GN OrderedLocusNames=Hbut_1548;
OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5).
OC Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Pyrodictiaceae;
OC Hyperthermus.
OX NCBI_TaxID=415426;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5456 / JCM 9403 / PLM1-5;
RX PubMed=17350933; DOI=10.1155/2007/745987;
RA Bruegger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M.,
RA She Q., Garrett R.A., Klenk H.-P.;
RT "The genome of Hyperthermus butylicus: a sulfur-reducing, peptide
RT fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
RL Archaea 2:127-135(2007).
CC -!- FUNCTION: RNA-free RNase P that catalyzes the removal of the 5'-leader
CC sequence from pre-tRNA to produce the mature 5'-terminus.
CC {ECO:0000255|HAMAP-Rule:MF_01078}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01078};
CC -!- SIMILARITY: Belongs to the HARP family. {ECO:0000255|HAMAP-
CC Rule:MF_01078}.
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DR EMBL; CP000493; ABM81369.1; -; Genomic_DNA.
DR RefSeq; WP_011822687.1; NC_008818.1.
DR AlphaFoldDB; A2BN08; -.
DR STRING; 415426.Hbut_1548; -.
DR EnsemblBacteria; ABM81369; ABM81369; Hbut_1548.
DR GeneID; 4782156; -.
DR KEGG; hbu:Hbut_1548; -.
DR eggNOG; arCOG00720; Archaea.
DR HOGENOM; CLU_109672_0_0_2; -.
DR OMA; YIIKKPP; -.
DR OrthoDB; 68994at2157; -.
DR Proteomes; UP000002593; Chromosome.
DR GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01078; RNA_free_RNase_P; 1.
DR InterPro; IPR014856; RNA_free_RNase_P.
DR PANTHER; PTHR41173; PTHR41173; 1.
DR Pfam; PF08745; PIN_5; 1.
DR TIGRFAMs; TIGR03875; RNA_lig_partner; 1.
PE 3: Inferred from homology;
KW Endonuclease; Hydrolase; Nuclease; Reference proteome; tRNA processing.
FT CHAIN 1..238
FT /note="RNA-free ribonuclease P"
FT /id="PRO_0000366692"
SQ SEQUENCE 238 AA; 26532 MW; 224DF5E9573B9821 CRC64;
MAEARLQRLL RVYVLDTSAL TDTRLRSLLG SGSLDEAVRR FAELIASVRI AYGVEVYMPP
TVYEEARRFL LSNGVTVQSF EALAAWITIK PPTRHEIRIP ASIVRDYVEE VRARLARGLR
VAEEHVRRAF EAGGLYAAET ASREARREKL GAIIRGLRER YREATRHGML DSVEDLDAVL
LALEVRGVLV SNDEGVRRFA EALGVISIDP PKFISVLQGL LRHSKTGGVA REEAHSTS