ID   RFRNP_THEYD             Reviewed;         196 AA.
AC   B5YIK6;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=RNA-free ribonuclease P {ECO:0000255|HAMAP-Rule:MF_01078};
DE            Short=RNA-free RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
DE            EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_01078};
DE   AltName: Full=Protein-only RNase P {ECO:0000255|HAMAP-Rule:MF_01078};
GN   OrderedLocusNames=THEYE_A0318;
OS   Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87).
OC   Bacteria; Nitrospirae; Thermodesulfovibrionia; Thermodesulfovibrionales;
OC   Thermodesulfovibrionaceae; Thermodesulfovibrio.
OX   NCBI_TaxID=289376;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51303 / DSM 11347 / YP87;
RA   Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.;
RT   "The complete genome sequence of Thermodesulfovibrio yellowstonii strain
RT   ATCC 51303 / DSM 11347 / YP87.";
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA-free RNase P that catalyzes the removal of the 5'-leader
CC       sequence from pre-tRNA to produce the mature 5'-terminus.
CC       {ECO:0000255|HAMAP-Rule:MF_01078}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01078};
CC   -!- SIMILARITY: Belongs to the HARP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01078}.
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DR   EMBL; CP001147; ACI20493.1; -; Genomic_DNA.
DR   RefSeq; WP_012545229.1; NC_011296.1.
DR   RefSeq; YP_002248165.1; NC_011296.1.
DR   AlphaFoldDB; B5YIK6; -.
DR   SMR; B5YIK6; -.
DR   STRING; 289376.THEYE_A0318; -.
DR   EnsemblBacteria; ACI20493; ACI20493; THEYE_A0318.
DR   KEGG; tye:THEYE_A0318; -.
DR   PATRIC; fig|289376.4.peg.311; -.
DR   eggNOG; COG1458; Bacteria.
DR   HOGENOM; CLU_109672_0_0_0; -.
DR   InParanoid; B5YIK6; -.
DR   OMA; YIIKKPP; -.
DR   OrthoDB; 1359470at2; -.
DR   Proteomes; UP000000718; Chromosome.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01078; RNA_free_RNase_P; 1.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR014856; RNA_free_RNase_P.
DR   PANTHER; PTHR41173; PTHR41173; 1.
DR   Pfam; PF08745; PIN_5; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
DR   TIGRFAMs; TIGR03875; RNA_lig_partner; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; tRNA processing.
FT   CHAIN           1..196
FT                   /note="RNA-free ribonuclease P"
FT                   /id="PRO_0000366690"
SQ   SEQUENCE   196 AA;  23158 MW;  3691E2B415498C65 CRC64;
     MINFFRKKRK IVLDTSVFIN PDIRNFFGEN PEKAIEEFIK IAKRAKNLEF YIPSTVFKEL
     MYFVDEKKIP KDFYFLIRIK SPDKHRSVCP AIFFYELVEE MRQRINKGLR VAENAVRNVN
     QKDADEIIKD LRKKYREALR EGIIDSKEDV DLIFLSMELQ ATLITGDQGL IKWADKLGIE
     WIVPEKFKDF LLSAIG