ID   RFS1_CAEBR              Reviewed;         244 AA.
AC   A8XP91;
DT   13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=RAD51-like protein 1 {ECO:0000250|UniProtKB:P34348};
GN   Name=rfs-1 {ECO:0000312|EMBL:CAP34571.1}; ORFNames=CBG16660;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP34571.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP34571.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Has a role in the homologous recombination repair (HRR) of
CC       genomic DNA during meiosis. Required for rad-51 recruitment onto ssDNA
CC       gaps generated at stalled replication fork barriers (By similarity).
CC       {ECO:0000250|UniProtKB:P34348}.
CC   -!- SUBUNIT: Interacts with brc-2 and rad-51.
CC       {ECO:0000250|UniProtKB:P34348}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HE600949; CAP34571.1; -; Genomic_DNA.
DR   RefSeq; XP_002641954.1; XM_002641908.1.
DR   AlphaFoldDB; A8XP91; -.
DR   SMR; A8XP91; -.
DR   STRING; 6238.CBG16660; -.
DR   EnsemblMetazoa; CBG16660.1; CBG16660.1; WBGene00036540.
DR   GeneID; 8583948; -.
DR   KEGG; cbr:CBG_16660; -.
DR   CTD; 8583948; -.
DR   WormBase; CBG16660; CBP18797; WBGene00036540; Cbr-rfs-1.
DR   eggNOG; ENOG502T0IA; Eukaryota.
DR   HOGENOM; CLU_987747_0_0_1; -.
DR   InParanoid; A8XP91; -.
DR   OMA; HITHWRG; -.
DR   OrthoDB; 1394413at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   GO; GO:0033063; C:Rad51B-Rad51C-Rad51D-XRCC2 complex; IBA:GO_Central.
DR   GO; GO:0005657; C:replication fork; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IBA:GO_Central.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0051117; F:ATPase binding; IEA:EnsemblMetazoa.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0000730; P:DNA recombinase assembly; IEA:EnsemblMetazoa.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:GO_Central.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IEA:EnsemblMetazoa.
DR   GO; GO:0042148; P:strand invasion; IBA:GO_Central.
DR   GO; GO:0000723; P:telomere maintenance; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   Pfam; PF08423; Rad51; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50162; RECA_2; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..244
FT                   /note="RAD51-like protein 1"
FT                   /id="PRO_0000386433"
SQ   SEQUENCE   244 AA;  27424 MW;  45A6B9F07E0210BE CRC64;
     MDSSKITFEY ETAYELLVRL GADGLFLHTS LPTLNKVLEL VPGKCYELDG DIGSGKTQLC
     YSLAAKLLLT KKTAKIGWIS AVPLRTDHLS QHISSTDADE TSHLLDRIVC KRVEMVSELR
     DSLNALCETI NMQLVIVENI DAILHDTAYD REMGRNVQID ISERLRKLTR SGITVMVTNH
     ITYWRGYPAP ALGNFWASQI ENRFFVERRS EESNVRSVST MRGGNEKTIR VDFEISDGGL
     KAVV