ID   RFT1_CANGA              Reviewed;         551 AA.
AC   Q6FPE8;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Oligosaccharide translocation protein RFT1;
GN   Name=RFT1; OrderedLocusNames=CAGL0J04378g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May participate in the translocation of oligosaccharide from
CC       the cytoplasmic side to the lumenal side of the endoplasmic reticulum
CC       membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RFT1 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG60845.1; -; Genomic_DNA.
DR   RefSeq; XP_447896.1; XM_447896.1.
DR   AlphaFoldDB; Q6FPE8; -.
DR   SMR; Q6FPE8; -.
DR   STRING; 5478.XP_447896.1; -.
DR   EnsemblFungi; CAG60845; CAG60845; CAGL0J04378g.
DR   GeneID; 2889634; -.
DR   KEGG; cgr:CAGL0J04378g; -.
DR   CGD; CAL0132928; CAGL0J04378g.
DR   VEuPathDB; FungiDB:CAGL0J04378g; -.
DR   eggNOG; KOG2864; Eukaryota.
DR   HOGENOM; CLU_023360_3_0_1; -.
DR   InParanoid; Q6FPE8; -.
DR   OMA; WPGKLFG; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0034203; P:glycolipid translocation; IEA:EnsemblFungi.
DR   InterPro; IPR007594; RFT1.
DR   PANTHER; PTHR13117; PTHR13117; 1.
DR   Pfam; PF04506; Rft-1; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..551
FT                   /note="Oligosaccharide translocation protein RFT1"
FT                   /id="PRO_0000212416"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        391..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        421..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        448..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        489..509
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        510..530
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   551 AA;  63121 MW;  88CCCC70DFD3B94C CRC64;
     MSGADILEKT TRGATFLMMG QLFSKIVTFL LNNTLVRYLS PRIFGITAFL EFIVGTVLFF
     SREAIRLSTQ RIADGNDADN DHDHDRDDSA LQVCVNFAMI PLFIGIPLSI GLIAWQYHNI
     NGYFVTLPFF QWSVFAIWVG IILELVNEPL FVLNQHFLNY GARSRYESIA VTANCLVNFT
     VVYSYEKKLI LTSYFDDSER FREGIAILAF ALGKLAYAAT LLMCYYYNYL MNFKSNKPFK
     LSLQKIKSKV NEKQTYYFRS DILEHFKKVY FQLCFKHLLT EGDKLIINTF CTVEEQGIYS
     LLSNYGSLIT RLLFAPIEES LRLLLAVLLS KKDSKNLQLS MKVLVNLTKF YLYLSLLVMI
     FGPNNSSYLL QFLIGSKWST NSVLHAIRVY CVYIPFLSFN GIFEAFLASV ATGDQILRHS
     YFMMMCSFAF LINSWIFIEY LDLSVNGLII SNIINMSLRI IYSFSFIVKF YRELHTESSI
     FMNFTNFKAT LGAAALVAIL NWQMVGYVSS FNGFITSATL ALILLSVILI KERATLNELI
     INRRAANMKS V