ID   RGG_STRGC               Reviewed;         297 AA.
AC   P49330; A8AVK2;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=HTH-type transcriptional regulator rgg;
GN   Name=rgg; OrderedLocusNames=SGO_0496;
OS   Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS   DL1 / V288).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=467705;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1534326; DOI=10.1128/jb.174.11.3577-3586.1992;
RA   Sulavik M.C., Tardif G., Clewell D.B.;
RT   "Identification of a gene, rgg, which regulates expression of
RT   glucosyltransferase and influences the Spp phenotype of Streptococcus
RT   gordonii Challis.";
RL   J. Bacteriol. 174:3577-3586(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288;
RX   PubMed=17720781; DOI=10.1128/jb.01023-07;
RA   Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT   "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT   to competence signaling peptide.";
RL   J. Bacteriol. 189:7799-7807(2007).
CC   -!- FUNCTION: Regulates the expression of glucosyltransferase (gtfG).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR   EMBL; M89776; AAA26968.1; -; Genomic_DNA.
DR   EMBL; CP000725; ABV10604.1; -; Genomic_DNA.
DR   PIR; A41898; A41898.
DR   AlphaFoldDB; P49330; -.
DR   SMR; P49330; -.
DR   STRING; 467705.SGO_0496; -.
DR   EnsemblBacteria; ABV10604; ABV10604; SGO_0496.
DR   KEGG; sgo:SGO_0496; -.
DR   eggNOG; COG1396; Bacteria.
DR   HOGENOM; CLU_072045_1_2_9; -.
DR   OMA; EFLRYEC; -.
DR   Proteomes; UP000001131; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR010057; Transcription_activator_MutR_C.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   TIGRFAMs; TIGR01716; RGG_Cterm; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..297
FT                   /note="HTH-type transcriptional regulator rgg"
FT                   /id="PRO_0000149734"
FT   DOMAIN          11..64
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        22..41
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   297 AA;  34439 MW;  A242D3BB3C67FF5E CRC64;
     MLIVKSSGKI LKIIRESKNM SLKEVAAGDI SVAQLSRYER GISSLTVDSF YSCLRNMSVS
     LAEFQYVYHN YREADDVVLS QKLSEAQREN NIVKLESILA GSEAMAQEFP EKKNYKLNTI
     VIRATLTSCN PDYQVSKGDI EFLTDYLFSV EEWGRYELWL FTNSVNLLTL ETLETFASEM
     INRTQFYNNL PENRRRIIKM LLNVVSACIE NNHLQVAMKF LNYIDNTKIP ETDLYDRVLI
     KYHKALYSYK VGNPHARHDI EQCLSTFEYL DSFGVARKLK EQFERIQLTV VADLQIE