RGMG2_BURL3
ID RGMG2_BURL3 Reviewed; 527 AA.
AC Q39HA1;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Putative ribose/galactose/methyl galactoside import ATP-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_01717};
DE EC=7.5.2.11 {ECO:0000255|HAMAP-Rule:MF_01717};
DE EC=7.5.2.7 {ECO:0000255|HAMAP-Rule:MF_01717};
GN OrderedLocusNames=Bcep18194_A4569;
OS Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS R18194 / 383).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=482957;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of an ABC transporter complex involved in carbohydrate
CC import. Could be involved in ribose, galactose and/or methyl
CC galactoside import. Responsible for energy coupling to the transport
CC system. {ECO:0000255|HAMAP-Rule:MF_01717}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29903, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:47013, ChEBI:CHEBI:456216; EC=7.5.2.7;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01717};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-galactose(out) + H2O = ADP + D-galactose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:60156, ChEBI:CHEBI:4139, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:456216; EC=7.5.2.11; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01717};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01717}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01717}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Carbohydrate
CC importer 2 (CUT2) (TC 3.A.1.2) family. {ECO:0000255|HAMAP-
CC Rule:MF_01717}.
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DR EMBL; CP000151; ABB08165.1; -; Genomic_DNA.
DR RefSeq; WP_011351735.1; NC_007510.1.
DR AlphaFoldDB; Q39HA1; -.
DR SMR; Q39HA1; -.
DR EnsemblBacteria; ABB08165; ABB08165; Bcep18194_A4569.
DR GeneID; 45094464; -.
DR KEGG; bur:Bcep18194_A4569; -.
DR PATRIC; fig|482957.22.peg.1473; -.
DR HOGENOM; CLU_000604_92_2_4; -.
DR OMA; EGMAVIM; -.
DR OrthoDB; 551294at2; -.
DR Proteomes; UP000002705; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015611; F:ABC-type D-ribose transporter activity; IEA:RHEA.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51260; MGLA; 1.
DR PROSITE; PS51254; RBSA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT CHAIN 1..527
FT /note="Putative ribose/galactose/methyl galactoside import
FT ATP-binding protein 2"
FT /id="PRO_0000262978"
FT DOMAIN 38..274
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01717"
FT DOMAIN 284..523
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01717"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 70..77
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01717"
SQ SEQUENCE 527 AA; 57688 MW; 2E90DE9CF2600B0D CRC64;
MFTARVARPM AGDDAPAASS GSTGSSAPPA SSAADCVLEV RGVGKSFPGV VALDGVQFRV
RRGTVHALMG ENGAGKSTLM KIIAGVYTPD QGEILINGEP VVLNGPLDAL DRGIAMIHQE
LNLMPYMTVA ENIWIRREPK NRFGLIDHAA LRRQTAELFE RLSIDIDPET DVRTLTVASR
QMVEIAKAVS FDSDVLIMDE PTSALTDKEV THLFRIIRQL REQGKGIVYI THKMNELFEI
ADEFSVFRDG KYIGTHASSD VTRDDIIRMM VGREITQMFP KEEVPIGDVV LSVKNLGVDG
VFRDVSFELR AGEILGVAGL VGSGRSNVAE ALFGVVPATS GEIRIDGKPV RITTPGQAMK
HGMAFLTEDR KDTGCFLNLD LLANMEAAVL SNRYVKFNFV RQAQLKRDCE EMSRMLRVKS
PGLHEEIQNL SGGNQQKVLI GRWLLTQPRI LILDEPTRGI DVGAKAEIHR LVSALAGKGV
AVLMISSEMP EVLGMSDRVM VMHEGRMTGI VDRKDADQVR IMDLASR
