ID   RGS11_CAEEL             Reviewed;         274 AA.
AC   O45524;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Regulator of G-protein signaling rgs-11;
GN   Name=rgs-11; ORFNames=F45B8.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
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DR   EMBL; Z83227; CAB05728.1; -; Genomic_DNA.
DR   PIR; T22214; T22214.
DR   RefSeq; NP_510483.1; NM_078082.4.
DR   AlphaFoldDB; O45524; -.
DR   SMR; O45524; -.
DR   STRING; 6239.F45B8.1; -.
DR   PaxDb; O45524; -.
DR   EnsemblMetazoa; F45B8.1.1; F45B8.1.1; WBGene00004354.
DR   GeneID; 181590; -.
DR   KEGG; cel:CELE_F45B8.1; -.
DR   UCSC; F45B8.1; c. elegans.
DR   CTD; 181590; -.
DR   WormBase; F45B8.1; CE10428; WBGene00004354; rgs-11.
DR   eggNOG; KOG3589; Eukaryota.
DR   GeneTree; ENSGT00970000196865; -.
DR   HOGENOM; CLU_1031475_0_0_1; -.
DR   InParanoid; O45524; -.
DR   OrthoDB; 240381at2759; -.
DR   PhylomeDB; O45524; -.
DR   Reactome; R-CEL-416476; G alpha (q) signalling events.
DR   Reactome; R-CEL-418594; G alpha (i) signalling events.
DR   PRO; PR:O45524; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00004354; Expressed in embryo and 3 other tissues.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.167.10; -; 1.
DR   InterPro; IPR016137; RGS.
DR   InterPro; IPR036305; RGS_sf.
DR   InterPro; IPR044926; RGS_subdomain_2.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; SSF48097; 1.
DR   PROSITE; PS50132; RGS; 1.
PE   4: Predicted;
KW   Reference proteome; Signal transduction inhibitor.
FT   CHAIN           1..274
FT                   /note="Regulator of G-protein signaling rgs-11"
FT                   /id="PRO_0000223576"
FT   DOMAIN          137..256
FT                   /note="RGS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00171"
SQ   SEQUENCE   274 AA;  31743 MW;  76E3742FEB47CFBA CRC64;
     MSIAITSPCQ IFPAIINADV YEKNLKVDDN AINVSKYSDN SVSLPTLSYE DFHHFSVVRH
     WNILFPYRLA TEWNWESRRL RKRDALVILE LVALSDETNK RGSVSRIMNT VRSKVHLMFS
     SSTELPSFQE IENWKKSPGL LAASKYGCAL FIQFLKQQTS ENEVDFWLDC QKFRSSTAKI
     SWKNKEVHRI LDQFLSSSAP RKIDMETSIL ARCMEYVEHI EGWKYTFDVA QAYVGLKFPK
     ESHKKFLEDP LYLDLLELVI SGRSCNKVGH KKSC