RH41_ORYSJ
ID RH41_ORYSJ Reviewed; 536 AA.
AC Q0E2Z7; B7EKP2; Q6Z785;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 2.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=DEAD-box ATP-dependent RNA helicase 41;
DE EC=3.6.4.13;
GN OrderedLocusNames=Os02g0201900, LOC_Os02g10770; ORFNames=P0419A09.31;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD box
CC family of RNA helicases and controls ATP binding and hydrolysis.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX59 subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF08141.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP004869; BAD15860.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF08141.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; BAS77523.1; -; Genomic_DNA.
DR EMBL; AK072368; BAG92939.1; -; mRNA.
DR EMBL; AK120266; BAG99943.1; -; mRNA.
DR RefSeq; XP_015627193.1; XM_015771707.1.
DR AlphaFoldDB; Q0E2Z7; -.
DR SMR; Q0E2Z7; -.
DR STRING; 4530.OS02T0201900-01; -.
DR PaxDb; Q0E2Z7; -.
DR PRIDE; Q0E2Z7; -.
DR EnsemblPlants; Os02t0201900-01; Os02t0201900-01; Os02g0201900.
DR GeneID; 4328652; -.
DR Gramene; Os02t0201900-01; Os02t0201900-01; Os02g0201900.
DR KEGG; osa:4328652; -.
DR eggNOG; KOG0331; Eukaryota.
DR HOGENOM; CLU_003041_1_5_1; -.
DR InParanoid; Q0E2Z7; -.
DR OMA; DESFCIR; -.
DR OrthoDB; 400908at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR ExpressionAtlas; Q0E2Z7; baseline and differential.
DR Genevisible; Q0E2Z7; OS.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR InterPro; IPR007529; Znf_HIT.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04438; zf-HIT; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Helicase; Hydrolase; Metal-binding; Nucleotide-binding;
KW Reference proteome; RNA-binding; Zinc; Zinc-finger.
FT CHAIN 1..536
FT /note="DEAD-box ATP-dependent RNA helicase 41"
FT /id="PRO_0000282510"
FT DOMAIN 168..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 355..518
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT ZN_FING 40..69
FT /note="HIT-type"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 137..165
FT /note="Q motif"
FT MOTIF 293..296
FT /note="DEAD box"
FT BINDING 181..188
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 536 AA; 59046 MW; 61DF6E454B6B3C13 CRC64;
MEQEENHSAD HLSAQPGNGN ELEESSVKER CFEQREALVG EPRCVICGRY GEYICDQTDD
DICSVECKTI LLSKLSAETR PVVKAAKRVN LPVGDESFCI RDENFPKIPS MHDGQIASLR
SKLDICVKGE DVPDPIMCFS SSGLPEKLVL NLEAAGYVMP TPVQMQVIPS SICNRSLLVS
ADTGSGKTAS FLVPIIAHCS HVRSERCTDK QGPLAIVLAP TRELCLQVEE QAKVLGKGLP
FKTALVVGGD PLAQQIYRIE NGIELIVGTP GRLIDLLMKH NVDLNKVDVF VLDEVDCLLE
RGFRDQVMQI FQALSHPQVM MFSATVNSEV EKMSNSLAKN AIHISCGNPS RPNKSVKQVV
IWVESKQKKQ KIFEIMTSKQ HFKPPAVVFV SSRIGADLLS EAITVATGLK VVSIHGDKTM
NERRESLRRF LTGEVSVVVC TGVLGRGMDL LKVRQVILFD MPNSIDEYVH QVGRASRMGV
EGMAIVFVNE EDRNLFRELV QILKTAGAPI PRELANSKYT TGIPLGGGKK RKLKSR
