RH48_ORYSJ
ID RH48_ORYSJ Reviewed; 811 AA.
AC Q6K7R9; B9F4M0;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=DEAD-box ATP-dependent RNA helicase 48;
DE EC=3.6.4.13;
GN OrderedLocusNames=Os02g0826100, LOC_Os02g57980;
GN ORFNames=OsJ_08955 {ECO:0000312|EMBL:EEE58088.1}, P0452F04.14;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD box
CC family of RNA helicases and controls ATP binding and hydrolysis.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK101090; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AP004776; BAD23043.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF10498.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS81691.1; -; Genomic_DNA.
DR EMBL; CM000139; EEE58088.1; -; Genomic_DNA.
DR EMBL; AK101090; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015626491.1; XM_015771005.1.
DR AlphaFoldDB; Q6K7R9; -.
DR SMR; Q6K7R9; -.
DR STRING; 4530.OS02T0826100-01; -.
DR PaxDb; Q6K7R9; -.
DR PRIDE; Q6K7R9; -.
DR EnsemblPlants; Os02t0826100-01; Os02t0826100-01; Os02g0826100.
DR GeneID; 4331214; -.
DR Gramene; Os02t0826100-01; Os02t0826100-01; Os02g0826100.
DR KEGG; osa:4331214; -.
DR eggNOG; KOG0342; Eukaryota.
DR HOGENOM; CLU_003041_26_6_1; -.
DR InParanoid; Q6K7R9; -.
DR OMA; MMPLIAR; -.
DR OrthoDB; 537587at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K7R9; OS.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Helicase; Hydrolase; Nucleotide-binding;
KW Reference proteome; RNA-binding.
FT CHAIN 1..811
FT /note="DEAD-box ATP-dependent RNA helicase 48"
FT /id="PRO_0000282518"
FT DOMAIN 373..556
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 570..740
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 286..333
FT /evidence="ECO:0000255"
FT MOTIF 342..370
FT /note="Q motif"
FT MOTIF 504..507
FT /note="DEAD box"
FT COMPBIAS 119..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 386..393
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT CONFLICT 233
FT /note="L -> F (in Ref. 5; AK101090)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 811 AA; 91802 MW; 6E13798FD57887F2 CRC64;
MGGGPRTFPG GLSKWQHKRM HEKLARHKER GLLRHEKQLY LARLRSEIRA SRLPAAGASP
PDDGDGPTSS RAHIRALADR FLLPGAEDLW NEDDGPIHRA DRPRPPRRIV SVGGNGGDRR
KLDSTKQELP RGGKEPRLAA FNPRRDFQTA APWWWQWSSS SAIPSRTKEA SFCFFGPKRS
YSVMPLFQAH QESSGTSMVP LIARGLASAR IAPSQLNGER FYSFAAGRFG RKLRPDSSDE
DDEDISTAKK DMRFARFGAS SEEESGYDEL EARSAIRKKW SSAALRNCDM KKERRALKSY
EEENNDLAGS FRELREEIKN REVLGAERRR YESRGESLFT NKRFEECGIS PLTVKALTDA
GYVQTTVVQE TALPMCLEGK DVLVKAKTGT GKSAAFLLPA IESVLNAMKS HTNHRVSPIF
SLILCPTREL AIQLTAEANV LLKYHQGIGV QSLIGGTRFK LDQRRLESDP CQILVATPGR
LLDHIENKSS FSVRLMGLKL LVLDEADHLL DLGFRTDIEK IVDSLPRQRQ TLLFSATIPK
EVRRVSQLVL KRDHVFVDTV GLGAVETPTK VEQLYLVMPH ELHFHMVYRL LREHIDQEVD
YKVIVFCTTA MVTEFMYIML RDLKLNVREI HSRKPQLYRT RISEEFRDSS RLILVTSDVS
TRGVNYPGVT LVIQVGVPSD REHYIHRLGR TGREGKSGKG ILLLAPWEEY FLNEIHDLPV
QKSQTPNIDE EMKRKVDGSI KIVDMSIKEA AYHAWLGYYN SIGDVGRDKT MLVDLANRFC
KSIGLEKPPA LYRKTALKMG LKDVPGIRIR K
