RH52C_ORYSJ
ID RH52C_ORYSJ Reviewed; 623 AA.
AC Q2R1M8; A0A0P0Y426;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=DEAD-box ATP-dependent RNA helicase 52C;
DE EC=3.6.4.13;
GN OrderedLocusNames=Os11g0599500, LOC_Os11g38670;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD box
CC family of RNA helicases and controls ATP binding and hydrolysis.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX3/DED1
CC subfamily. {ECO:0000305}.
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DR EMBL; DP000010; ABA94715.1; -; Genomic_DNA.
DR EMBL; AP008217; BAF28584.1; -; Genomic_DNA.
DR EMBL; AP014967; BAT14744.1; -; Genomic_DNA.
DR RefSeq; XP_015617825.1; XM_015762339.1.
DR AlphaFoldDB; Q2R1M8; -.
DR SMR; Q2R1M8; -.
DR STRING; 4530.OS11T0599500-00; -.
DR PaxDb; Q2R1M8; -.
DR PRIDE; Q2R1M8; -.
DR EnsemblPlants; Os11t0599500-00; Os11t0599500-00; Os11g0599500.
DR GeneID; 4350856; -.
DR Gramene; Os11t0599500-00; Os11t0599500-00; Os11g0599500.
DR KEGG; osa:4350856; -.
DR eggNOG; KOG0335; Eukaryota.
DR HOGENOM; CLU_003041_16_3_1; -.
DR InParanoid; Q2R1M8; -.
DR OMA; NQNIVKG; -.
DR OrthoDB; 595675at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q2R1M8; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IBA:GO_Central.
DR CDD; cd17967; DEADc_DDX3_DDX4; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR044763; Ded1/Dbp1_DEADc.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome;
KW RNA-binding.
FT CHAIN 1..623
FT /note="DEAD-box ATP-dependent RNA helicase 52C"
FT /id="PRO_0000282452"
FT DOMAIN 186..372
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 399..550
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 155..183
FT /note="Q motif"
FT MOTIF 316..319
FT /note="DEAD box"
FT COMPBIAS 59..73
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 199..206
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 623 AA; 65988 MW; 0F16AB3645351C3D CRC64;
MATPSRTSWA DVADADPAPA PAPAANGPAR PDRSSYVPPH LRNRGASSGG GAAAPPPSSS
SSSAPPPRAA PGLLAPRPAA AGMGRMGGGG GGGGFGGPRR WDREPNPFGN DGDAAAGAGD
EPEVFDAHQN TGINFDAYED IPVETSGREV PPPVGTFAEI DLGQALNDNI RRCKYVRPTP
VQRYAIPISL AGRDLMACAQ TGSGKTAAFC FPIISGIMRG PPAQRPQRGG MRTACPLALI
LSPTRELSMQ IHEEARKFSY QTGVRVVVAY GGAPINQQLR DLERGVDILV ATPGRLVDLL
ERARVSLQSI RYLALDEADR MLDMGFEPQV RRIVEQMDMP PPGARQTMLF SATFPKEIQR
MASDFLENYI FLAVGRVGSS TDLIVQRVEF VQEADKRSHL MDLLHAQRDS ATPGKPTLTL
VFVETKRGAD SLEHWLCMNG FPATSIHGDR NQQEREYALR SFKSGHTPIL VATDVAARGL
DIPHVAHVVN FDLPNDIDDY VHRIGRTGRA GKSGLATAFF NENNSSMARS LAELMQESNQ
EVPAWLSRYA ARPSYGGGGG RNRRSGGGSR FGGRDFRRDS SSGRGGGDYY GGGSSGGAGG
YGGSSAYGGG GYGGGAGAPS AWD
