ID   RHA1_RHOTO              Reviewed;          62 AA.
AC   P07907;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 2.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Rhodotorucin-A peptides type 1;
DE   Contains:
DE     RecName: Full=Rhodotorucin-A;
DE     AltName: Full=Rhodotorucine-A;
DE   Flags: Precursor;
GN   Name=RHA1; Synonyms=RHA;
OS   Rhodosporidium toruloides (Yeast) (Rhodotorula gracilis).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX   NCBI_TaxID=5286;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Akada R., Minomi K., Yamashita I., Miyakawa T., Fukui S.;
RT   "Cloning of a gene coding for rhodotorucine A, a farnesyl peptide mating
RT   pheromone of Rhodosporidium toruloides.";
RL   Agric. Biol. Chem. 51:1211-1215(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IFO 0559-M919;
RX   PubMed=2571924; DOI=10.1128/mcb.9.8.3491-3498.1989;
RA   Akada R., Minomi K., Kai J., Yamashita I., Miyakawa T., Fukui S.;
RT   "Multiple genes coding for precursors of rhodotorucine A, a farnesyl
RT   peptide mating pheromone of the basidiomycetous yeast Rhodosporidium
RT   toruloides.";
RL   Mol. Cell. Biol. 9:3491-3498(1989).
RN   [3]
RP   ISOPRENYLATION AT CYS-14; CYS-29; CYS-44 AND CYS-59.
RA   Kamiya Y., Sakurai A., Tamura S., Takahashi N., Abe K., Tsuchiya E.,
RA   Fukui S., Kitada C., Fujino M.;
RT   "Structure of rhodotorucine A, a novel lipopeptide, inducing mating tube
RT   formation in Rhodosporidium toruloides.";
RL   Biochem. Biophys. Res. Commun. 83:1077-1083(1978).
CC   -!- FUNCTION: Rhodotorucin-A is a mating pheromone in cells of mating type
CC       A of Rhodosporidium toruloides.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA00073.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M28121; AAA77660.1; -; Genomic_DNA.
DR   EMBL; D00119; BAA00073.1; ALT_INIT; Genomic_DNA.
DR   PIR; A32824; A32824.
DR   AlphaFoldDB; P07907; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Pheromone; Prenylation.
FT   PROPEP          1..3
FT                   /id="PRO_0000239408"
FT   PEPTIDE         4..14
FT                   /note="Rhodotorucin-A"
FT                   /id="PRO_0000022229"
FT   PROPEP          15..18
FT                   /id="PRO_0000239409"
FT   PEPTIDE         19..29
FT                   /note="Rhodotorucin-A"
FT                   /id="PRO_0000022230"
FT   PROPEP          30..33
FT                   /id="PRO_0000239410"
FT   PEPTIDE         34..44
FT                   /note="Rhodotorucin-A"
FT                   /id="PRO_0000022231"
FT   PROPEP          45..48
FT                   /id="PRO_0000239411"
FT   PEPTIDE         49..59
FT                   /note="Rhodotorucin-A"
FT                   /id="PRO_0000022232"
FT   PROPEP          60..62
FT                   /id="PRO_0000239412"
FT   SITE            14
FT                   /note="Not methylated"
FT   SITE            29
FT                   /note="Not methylated"
FT   SITE            44
FT                   /note="Not methylated"
FT   SITE            59
FT                   /note="Not methylated"
FT   LIPID           14
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000269|Ref.3"
FT   LIPID           29
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000269|Ref.3"
FT   LIPID           44
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000269|Ref.3"
FT   LIPID           59
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000269|Ref.3"
SQ   SEQUENCE   62 AA;  7067 MW;  7491A98304011B48 CRC64;
     MVAYPEISWT RNGCTVSKYP EISWTRNGCT VSKYPEISWT RNGCTVSKYP EISWTRNGCT
     VA