RHA3_RHOTO
ID RHA3_RHOTO Reviewed; 47 AA.
AC P20466; Q02087;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-1998, sequence version 2.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Rhodotorucin-A peptides type 3;
DE Contains:
DE RecName: Full=Rhodotorucin-A;
DE AltName: Full=Rhodotorucine-A;
DE Flags: Precursor;
GN Name=RHA3;
OS Rhodosporidium toruloides (Yeast) (Rhodotorula gracilis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=5286;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=IFO 0559-M919;
RX PubMed=2571924; DOI=10.1128/mcb.9.8.3491-3498.1989;
RA Akada R., Minomi K., Kai J., Yamashita I., Miyakawa T., Fukui S.;
RT "Multiple genes coding for precursors of rhodotorucine A, a farnesyl
RT peptide mating pheromone of the basidiomycetous yeast Rhodosporidium
RT toruloides.";
RL Mol. Cell. Biol. 9:3491-3498(1989).
RN [2]
RP ISOPRENYLATION AT CYS-14; CYS-29 AND CYS-44.
RA Kamiya Y., Sakurai A., Tamura S., Takahashi N., Abe K., Tsuchiya E.,
RA Fukui S., Kitada C., Fujino M.;
RT "Structure of rhodotorucine A, a novel lipopeptide, inducing mating tube
RT formation in Rhodosporidium toruloides.";
RL Biochem. Biophys. Res. Commun. 83:1077-1083(1978).
CC -!- FUNCTION: Rhodotorucin-A is a mating pheromone in cells of mating type
CC A of Rhodosporidium toruloides.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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DR EMBL; M28123; AAA77662.1; -; Genomic_DNA.
DR PIR; C32824; C32824.
DR AlphaFoldDB; P20466; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cell membrane; Lipoprotein; Membrane; Pheromone; Prenylation.
FT PROPEP 1..3
FT /id="PRO_0000239419"
FT PEPTIDE 4..14
FT /note="Rhodotorucin-A"
FT /id="PRO_0000022238"
FT PROPEP 15..18
FT /id="PRO_0000239420"
FT PEPTIDE 19..29
FT /note="Rhodotorucin-A"
FT /id="PRO_0000022239"
FT PROPEP 30..33
FT /id="PRO_0000239421"
FT PEPTIDE 34..44
FT /note="Rhodotorucin-A"
FT /id="PRO_0000022240"
FT PROPEP 45..47
FT /id="PRO_0000239422"
FT SITE 14
FT /note="Not methylated"
FT SITE 29
FT /note="Not methylated"
FT SITE 44
FT /note="Not methylated"
FT LIPID 14
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000269|Ref.2"
FT LIPID 29
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000269|Ref.2"
FT LIPID 44
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000269|Ref.2"
SQ SEQUENCE 47 AA; 5328 MW; 9FFF1B5C600AB08D CRC64;
MVAYPEISWT RNGCTVAKYP EISWTRNGCT VSKYPEISWT RNGCTVA