ID   RHAL_RHIME              Reviewed;         430 AA.
AC   Q92S14;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Probable sugar isomerase R00627;
DE            EC=5.3.1.-;
GN   OrderedLocusNames=R00627; ORFNames=SMc02321;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the rhamnose isomerase family. {ECO:0000305}.
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DR   EMBL; AL591688; CAC45199.1; -; Genomic_DNA.
DR   RefSeq; NP_384733.1; NC_003047.1.
DR   RefSeq; WP_010968713.1; NC_003047.1.
DR   AlphaFoldDB; Q92S14; -.
DR   SMR; Q92S14; -.
DR   STRING; 266834.SMc02321; -.
DR   EnsemblBacteria; CAC45199; CAC45199; SMc02321.
DR   GeneID; 61602094; -.
DR   KEGG; sme:SMc02321; -.
DR   PATRIC; fig|266834.11.peg.1999; -.
DR   eggNOG; COG4952; Bacteria.
DR   HOGENOM; CLU_059875_0_0_5; -.
DR   OMA; MIDQSHN; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR013451; L_rhamnose_iso.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR02629; L_rham_iso_rhiz; 1.
PE   3: Inferred from homology;
KW   Isomerase; Manganese; Metal-binding; Reference proteome.
FT   CHAIN           1..430
FT                   /note="Probable sugar isomerase R00627"
FT                   /id="PRO_0000090572"
FT   BINDING         257
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         289
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         291
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   430 AA;  46708 MW;  3BAEC74C642F1B1E CRC64;
     MTLMISTSVL DAENASRRDA LTRDYESLGD RLARRGIDID AVKAKVAAYG VAVPSWGVGT
     GGTRFARFPG PGEPRNIFDK LEDCAVIQQL TRATPAVSLH IPWDKVSDLG ALKEKGSALG
     LSFDAMNSNT FSDAPGQAHS YKFGSLSHTD SATRRQAIEH NLECVEIGKA LGSKALTVWV
     GDGSNFPGQS NFTRAFERYL DSMKAVYAAL PDDWRIFTEH KMFEPAFYST VVQDWGTNYL
     IAQELGPKAF CLVDLGHHAP NVNIEMIVAR LIQFKKLGGF HFNDSKYGDD DLDTGSIDPY
     RLFLVFNELV DAETRAANGF DPAHMLDQSH NVTDPIESLM TSAMEVGRAY AQALIVDRKA
     LAGYQEENDA LMASETLKTA FRTDVEPILA TARLENDGAI APVAAYRASG YRARVAAERP
     AVAGGGGGIV