ID   RHAMA_LACRH             Reviewed;          13 AA.
AC   P86526;
DT   15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Bacteriocin rhamnosin A {ECO:0000303|PubMed:19796123};
DE   Flags: Fragment;
OS   Lacticaseibacillus rhamnosus (Lactobacillus rhamnosus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=47715;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY.
RC   STRAIN=68 {ECO:0000269|PubMed:19796123};
RX   PubMed=19796123; DOI=10.1111/j.1365-2672.2009.04539.x;
RA   Dimitrijevic R., Stojanovic M., Zivkovic I., Petersen A., Jankov R.M.,
RA   Dimitrijevic L., Gavrovic-Jankulovic M.;
RT   "The identification of a low molecular mass bacteriocin, rhamnosin A,
RT   produced by Lactobacillus rhamnosus strain 68.";
RL   J. Appl. Microbiol. 107:2108-2115(2009).
CC   -!- FUNCTION: Antibacterial activity against the Gram-positive bacterium
CC       M.lysodeikticus. It may act as a pore-forming protein, creating a
CC       channel in the cell membrane. {ECO:0000269|PubMed:19796123}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19796123}.
CC   -!- MASS SPECTROMETRY: Mass=6433.7558; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:19796123};
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DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0051838; P:cytolysis by host of symbiont cells; IDA:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Secreted.
FT   CHAIN           1..>13
FT                   /note="Bacteriocin rhamnosin A"
FT                   /id="PRO_0000394468"
FT   UNSURE          2
FT                   /note="V or K"
FT                   /evidence="ECO:0000269|PubMed:19796123"
FT   UNSURE          3
FT                   /note="P or T"
FT                   /evidence="ECO:0000269|PubMed:19796123"
FT   NON_TER         13
FT                   /evidence="ECO:0000303|PubMed:19796123"
SQ   SEQUENCE   13 AA;  1414 MW;  727971F9CA54A324 CRC64;
     AVPAVRKTNE TLD