ID   RHAR_PECCP              Reviewed;         284 AA.
AC   C6DJR5;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=HTH-type transcriptional activator RhaR {ECO:0000255|HAMAP-Rule:MF_01533};
DE   AltName: Full=L-rhamnose operon transcriptional activator RhaR {ECO:0000255|HAMAP-Rule:MF_01533};
GN   Name=rhaR {ECO:0000255|HAMAP-Rule:MF_01533}; OrderedLocusNames=PC1_0422;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Activates expression of the rhaSR operon in response to L-
CC       rhamnose. {ECO:0000255|HAMAP-Rule:MF_01533}.
CC   -!- SUBUNIT: Binds DNA as a dimer. {ECO:0000255|HAMAP-Rule:MF_01533}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01533}.
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DR   EMBL; CP001657; ACT11478.1; -; Genomic_DNA.
DR   RefSeq; WP_012773134.1; NC_012917.1.
DR   AlphaFoldDB; C6DJR5; -.
DR   SMR; C6DJR5; -.
DR   STRING; 561230.PC1_0422; -.
DR   EnsemblBacteria; ACT11478; ACT11478; PC1_0422.
DR   KEGG; pct:PC1_0422; -.
DR   eggNOG; COG1917; Bacteria.
DR   eggNOG; COG4977; Bacteria.
DR   HOGENOM; CLU_000445_88_5_6; -.
DR   OMA; NREVGMT; -.
DR   OrthoDB; 1268974at2; -.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0019299; P:rhamnose metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.120.10; -; 1.
DR   HAMAP; MF_01533; HTH_type_RhaR; 1.
DR   InterPro; IPR003313; AraC-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   InterPro; IPR023699; Tscrpt_act_RhaR.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF02311; AraC_binding; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF51182; SSF51182; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Repeat; Rhamnose metabolism;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..284
FT                   /note="HTH-type transcriptional activator RhaR"
FT                   /id="PRO_1000215403"
FT   DOMAIN          181..279
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01533"
FT   DNA_BIND        198..219
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01533"
FT   DNA_BIND        246..269
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01533"
FT   SITE            248
FT                   /note="Interaction with sigma-70"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01533"
SQ   SEQUENCE   284 AA;  32839 MW;  3D7E5367DE6D8597 CRC64;
     MATAVRGLKL QTEDYFLTDK NVVMVAERHP QPVFPLHHHD FDELVIVWRG NGLHLWNDVP
     YRITRGDMFY VSANDRHSYE SVHGLELDNI LYIRNRLTLS ADWQRLLPGG EHPQSQRHWC
     LGSEGMDTLR EKVDALRQEC MKSDALSLQL SEALLLQIAL LAARYRHTPD NPQLADAHQL
     DMLMNALRAS IAAPFRFEAF CEQHHFSARS LRSRFKEQTG MSVPHYLRQL RLCKAMELLR
     YDLQTIGDIA ALCGFEDSNY FSVVFHQAFG VSPSAYRQRF LNVE