ID   RHAT_SALHS              Reviewed;         344 AA.
AC   B4TBY5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=L-rhamnose-proton symporter {ECO:0000255|HAMAP-Rule:MF_01532};
DE   AltName: Full=L-rhamnose-H(+) transport protein {ECO:0000255|HAMAP-Rule:MF_01532};
GN   Name=rhaT {ECO:0000255|HAMAP-Rule:MF_01532}; OrderedLocusNames=SeHA_C4379;
OS   Salmonella heidelberg (strain SL476).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454169;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL476;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Uptake of L-rhamnose across the cytoplasmic membrane with the
CC       concomitant transport of protons into the cell (symport system).
CC       {ECO:0000255|HAMAP-Rule:MF_01532}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+)(in) + L-rhamnopyranose(in) = H(+)(out) + L-
CC         rhamnopyranose(out); Xref=Rhea:RHEA:29947, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:62346; Evidence={ECO:0000255|HAMAP-Rule:MF_01532};
CC       PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:29949;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01532};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01532}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01532}.
CC   -!- SIMILARITY: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01532}.
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DR   EMBL; CP001120; ACF65916.1; -; Genomic_DNA.
DR   RefSeq; WP_000063541.1; NC_011083.1.
DR   AlphaFoldDB; B4TBY5; -.
DR   KEGG; seh:SeHA_C4379; -.
DR   HOGENOM; CLU_066437_0_0_6; -.
DR   OMA; QFFFYGM; -.
DR   Proteomes; UP000001866; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015153; F:rhamnose transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_01532; RhaT; 1.
DR   InterPro; IPR004673; L-rhamnose-proton_sym_RhaT.
DR   Pfam; PF06379; RhaT; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Sugar transport; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..344
FT                   /note="L-rhamnose-proton symporter"
FT                   /id="PRO_1000146498"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
SQ   SEQUENCE   344 AA;  37390 MW;  C9B90BD9BC9541D9 CRC64;
     MSNAITMGIF WHLIGAASAA CFYAPFKQVK QWSWETMWSV GGIVSWLILP WTISALLLPD
     FWAYYGQFNL STLLPVFLFG AMWGIGNINY GLTMRYLGMS MGIGIAIGIT LIVGTLMTPI
     INGNFDVLIH TEGGRMTLLG VFVALIGVGI VTRAGQLKER KMGIKAEEFN LKKGLLLAVM
     CGIFSAGMSF AMNAAKPMHE AAAALGVDPL YVALPSYVVI MGGGALVNLG FCFIRLAKVQ
     NLSIKADFSL ARPLIISNIL LSALGGLMWY LQFFFYAWGH ARIPAQYDYM SWMLHMSFYV
     LCGGLVGLVL KEWKNAGRRP VAVLSLGCVV IIIAANIVGL GMAS