ID   RHAT_YERPA              Reviewed;         343 AA.
AC   Q1C0W4;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=L-rhamnose-proton symporter {ECO:0000255|HAMAP-Rule:MF_01532};
DE   AltName: Full=L-rhamnose-H(+) transport protein {ECO:0000255|HAMAP-Rule:MF_01532};
GN   Name=rhaT {ECO:0000255|HAMAP-Rule:MF_01532}; OrderedLocusNames=YPA_3947;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Uptake of L-rhamnose across the cytoplasmic membrane with the
CC       concomitant transport of protons into the cell (symport system).
CC       {ECO:0000255|HAMAP-Rule:MF_01532}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+)(in) + L-rhamnopyranose(in) = H(+)(out) + L-
CC         rhamnopyranose(out); Xref=Rhea:RHEA:29947, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:62346; Evidence={ECO:0000255|HAMAP-Rule:MF_01532};
CC       PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:29949;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01532};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01532}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01532}.
CC   -!- SIMILARITY: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01532}.
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DR   EMBL; CP000308; ABG15908.1; -; Genomic_DNA.
DR   RefSeq; WP_002221177.1; NZ_CP009906.1.
DR   AlphaFoldDB; Q1C0W4; -.
DR   EnsemblBacteria; ABG15908; ABG15908; YPA_3947.
DR   KEGG; ypa:YPA_3947; -.
DR   OMA; QFFFYGM; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015153; F:rhamnose transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_01532; RhaT; 1.
DR   InterPro; IPR004673; L-rhamnose-proton_sym_RhaT.
DR   Pfam; PF06379; RhaT; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Sugar transport; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..343
FT                   /note="L-rhamnose-proton symporter"
FT                   /id="PRO_0000292769"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01532"
SQ   SEQUENCE   343 AA;  37311 MW;  A8544D0F0B12C02D CRC64;
     MNNAIILGII WHLVGAASAA CFYAPFKQVK KWSWETMWSI GGLVSWLILP WTVSYLLLPD
     FWQYYGSFSI ATLLPVFLFG AMWGIGNINY GLTMRYLGMS MGIGIAIGIT LIIGTLMTPI
     LQGRFDVLLG TPGGRMTLLG VFVALIGVAI VSYAGLLKER AMGIQAEEFN LKKGLILAVM
     CGIFSAGMSF AMDAAKPMHE AASALGINSL YVALPSYVII MGGGAIINLS YCFIRLATLK
     NLSVKADFSV AKPLLITNIL FSALAGLMWY LQFFYAWGHA KIPQQYDYMS WMLHMSFYVL
     CGGIVGLLLK EWKCSTKKPV AVLCIGCLVI ILAANIVGLG MAA