RHIP1_ARATH
ID RHIP1_ARATH Reviewed; 263 AA.
AC Q84K90; O65593;
DT 23-MAY-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=RGS1-HXK1-interacting protein 1 {ECO:0000303|PubMed:26528314};
GN Name=RHIP1 {ECO:0000303|PubMed:26528314};
GN OrderedLocusNames=At4g26410 {ECO:0000312|Araport:AT4G26410};
GN ORFNames=M3E9.160 {ECO:0000312|EMBL:CAA18229.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, AND BIOTECHNOLOGY.
RX PubMed=25345678; DOI=10.1038/srep06781;
RA Wang H., Wang J., Jiang J., Chen S., Guan Z., Liao Y., Chen F.;
RT "Reference genes for normalizing transcription in diploid and tetraploid
RT Arabidopsis.";
RL Sci. Rep. 4:6781-6781(2014).
RN [5]
RP FUNCTION, DISRUPTION PHENOTYPE, AND INTERACTION WITH RGS1 AND HXK1.
RC STRAIN=cv. Columbia;
RX PubMed=26528314; DOI=10.3389/fpls.2015.00851;
RA Huang J.-P., Tunc-Ozdemir M., Chang Y., Jones A.M.;
RT "Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein
RT pathway in Arabidopsis thaliana.";
RL Front. Plant Sci. 6:851-851(2015).
CC -!- FUNCTION: Required for some glucose-regulated gene expression, being a
CC physical connection between RGS1 and HXK1 in sugar signaling. Prevents
CC roots and inflorecences growth. {ECO:0000269|PubMed:26528314}.
CC -!- SUBUNIT: Interacts with RGS1 and HXK1. {ECO:0000269|PubMed:26528314}.
CC -!- TISSUE SPECIFICITY: Expressed constitutively.
CC {ECO:0000269|PubMed:25345678}.
CC -!- DISRUPTION PHENOTYPE: Long roots in young seedlings and large
CC inflorescences in adult plants. Arrested seedling development in
CC response to glucose. {ECO:0000269|PubMed:26528314}.
CC -!- BIOTECHNOLOGY: Proposed as a reliable reference gene for normalization
CC purposes. {ECO:0000269|PubMed:25345678}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA18229.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79496.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL022223; CAA18229.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161565; CAB79496.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE85195.1; -; Genomic_DNA.
DR EMBL; BT002964; AAO22774.1; -; mRNA.
DR EMBL; BT004440; AAO42434.1; -; mRNA.
DR PIR; T05063; T05063.
DR RefSeq; NP_194371.2; NM_118774.4.
DR AlphaFoldDB; Q84K90; -.
DR SMR; Q84K90; -.
DR STRING; 3702.AT4G26410.1; -.
DR iPTMnet; Q84K90; -.
DR PaxDb; Q84K90; -.
DR PRIDE; Q84K90; -.
DR ProteomicsDB; 236249; -.
DR EnsemblPlants; AT4G26410.1; AT4G26410.1; AT4G26410.
DR GeneID; 828747; -.
DR Gramene; AT4G26410.1; AT4G26410.1; AT4G26410.
DR KEGG; ath:AT4G26410; -.
DR Araport; AT4G26410; -.
DR TAIR; locus:2131473; AT4G26410.
DR eggNOG; ENOG502QQTD; Eukaryota.
DR HOGENOM; CLU_060640_0_0_1; -.
DR InParanoid; Q84K90; -.
DR OMA; STDSAMR; -.
DR OrthoDB; 1204838at2759; -.
DR PhylomeDB; Q84K90; -.
DR PRO; PR:Q84K90; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q84K90; baseline and differential.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0071333; P:cellular response to glucose stimulus; IMP:TAIR.
DR GO; GO:1902659; P:regulation of glucose mediated signaling pathway; IMP:UniProtKB.
DR InterPro; IPR016803; RHIP1.
DR PIRSF; PIRSF022280; UCP022280; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Reference proteome.
FT CHAIN 1..263
FT /note="RGS1-HXK1-interacting protein 1"
FT /id="PRO_0000444197"
SQ SEQUENCE 263 AA; 29201 MW; 0435A448B750AAFC CRC64;
MSETEATGVT DDSAPAIETE TVSDAMEHTA IGVVESVEGA IEGAEKWVGD LQRTVKESKD
TAMRSARSLR ENSTSQFRSI QDFIPHALTQ YKTYENAFFS KVTDELIYAK EHPAAAIGIG
VAASLVLMRG PRRFLFRNTL GRFQSEEAQF LKAEKHVQEL NMSVDLMKKE SRKLLERTAL
AEKDMKRGLS ELMNSGNDIH RLAKSVHKAE CEAADLMDGL RQIPGRDAIK LRAEVASMTS
LLRQKRIALN KRIMGMSDLG VSV
