ID   RHL1_LOTJA              Reviewed;         386 AA.
AC   D0PX88;
DT   17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=bHLH transcription factor RHL1 {ECO:0000303|PubMed:19675148};
DE   AltName: Full=Basic helix-loop-helix protein RHL1 {ECO:0000305};
DE   AltName: Full=Protein ROOT HAIRLESS 1 {ECO:0000303|PubMed:19675148};
DE            Short=LjRHL1 {ECO:0000303|PubMed:19675148};
GN   Name=RHL1 {ECO:0000303|PubMed:19675148};
OS   Lotus japonicus (Lotus corniculatus var. japonicus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; robinioid clade; Loteae; Lotus.
OX   NCBI_TaxID=34305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX   PubMed=19675148; DOI=10.1104/pp.109.143867;
RA   Karas B., Amyot L., Johansen C., Sato S., Tabata S., Kawaguchi M.,
RA   Szczyglowski K.;
RT   "Conservation of lotus and Arabidopsis basic helix-loop-helix proteins
RT   reveals new players in root hair development.";
RL   Plant Physiol. 151:1175-1185(2009).
CC   -!- FUNCTION: Transcription factor that regulates the development of root
CC       hairs. {ECO:0000269|PubMed:19675148}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981,
CC       ECO:0000269|PubMed:19675148}.
CC   -!- TISSUE SPECIFICITY: Expressed in root epidermal cells.
CC       {ECO:0000303|PubMed:19675148}.
CC   -!- DISRUPTION PHENOTYPE: Root-hairless phenotype.
CC       {ECO:0000269|PubMed:19675148}.
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DR   EMBL; FJ375304; ACP28172.1; -; Genomic_DNA.
DR   AlphaFoldDB; D0PX88; -.
DR   SMR; D0PX88; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..386
FT                   /note="bHLH transcription factor RHL1"
FT                   /id="PRO_0000450107"
FT   DOMAIN          180..229
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          119..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..193
FT                   /note="Basic motif; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          194..229
FT                   /note="Helix-loop-helix motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   COMPBIAS        119..165
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   386 AA;  40547 MW;  8D45E1D499A0CEA0 CRC64;
     MNNHHQQLNP QFDPTSHDDF LEQMLSTLPS FWDPNSDLSA ETTPDNVAAF PFDEHSTLNS
     KFRNHQITSP TTKAAAALML QQHLLQMPAN DVVDPTNFFK SPNPGGEASA SVQALYNGFT
     GSLNGTQPQQ HFQHPPQGNS NQIQGQNFGA TNQAPPASGS AGGGGNQGQA KPRVRARRGQ
     ATDPHSIAER LRRERIAERM KALQELVPNA NKTDKASMLD EIIDYVKFLQ LQVKVLSMSR
     LGGAAAVAPL VADISSEGGG GGGGGDCVTN GAGGVLPRST TTAASTTNDS LTMTEHQVAK
     LMEEDMGSAM QYLQGKGLCL MPISLATAIS TATCHTRSPL IPNNLANLAA AAASNGEGPS
     SPNMSVLTVQ SAVAGNDSTV KDVSKP