ID   RHLC_GORGO              Reviewed;         417 AA.
AC   Q28426;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=RH-like protein IC;
DE   AltName: Full=Rhesus-like protein IC;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Bone marrow;
RX   PubMed=7993375; DOI=10.1007/bf00554623;
RA   Salvignol I., Blancher A., Calvas P., Clayton J., Socha W.W., Colin Y.,
RA   Ruffie J.;
RT   "Molecular genetics of chimpanzee Rh-related genes: their relationship with
RT   the R-C-E-F blood group system, the chimpanzee counterpart of the human
RT   rhesus system.";
RL   Biochem. Genet. 32:201-221(1994).
CC   -!- FUNCTION: May be part of an oligomeric complex which is likely to have
CC       a transport or channel function in the erythrocyte membrane.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC       subfamily. {ECO:0000305}.
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DR   EMBL; L37052; AAA65626.1; -; mRNA.
DR   PIR; I37075; I37075.
DR   AlphaFoldDB; Q28426; -.
DR   SMR; Q28426; -.
DR   Proteomes; UP000001519; Unplaced.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0097272; P:ammonium homeostasis; IBA:GO_Central.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.10.3430.10; -; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   InterPro; IPR002229; RhesusRHD.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   PRINTS; PR00342; RHESUSRHD.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..417
FT                   /note="RH-like protein IC"
FT                   /id="PRO_0000168191"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   417 AA;  45261 MW;  FA92A6DFC8957C47 CRC64;
     MSSKYPRSVR CCLPLCALTL EAALILLFYF FTHYDASLED QKGLVASYQV GQDLTVMAAI
     GFGFLTSSFR RHSWSSVAFN LFMLALGVQW AILLDGFLSQ FPPGKVVITL FSIRLATMSA
     LSVLISAGAV LGYVNLVQLV VMVLVEVTAL GTMRMVISNI FNTDYHMNMT HFYVFAAYFG
     VTVAWCLPKP LPDIKEDKDQ IATIPSLSAM LGTLFLWMFW PSFNSALLRS PIERKNAVFN
     TYYALAVSVV TAISVSSLAH PQGKINMTYM HNAVLAGGVA VGTSCHLITS PWLAMVLGLV
     AGLISIGGAK CLPGCCNRVL GIHDSSVMHY NFSLLGLLGE ITYIVLMVLH TVGAGNGMVG
     FQVLVSTGEL SLALAIAVTS GLLTGLLLNL KIWKAPHAAK YFDDQVFWKF PHLAVGF